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Volume 22, Number 8—August 2016

Baylisascaris procyonis–Associated Meningoencephalitis in a Previously Healthy Adult, California, USA

Charles LangelierComments to Author , Michael J. Reid, Cathra Halabi, Natalie Witek, Alejandro LaRiviere, Maulik Shah, Michael R. Wilson, Peter Chin-Hong, Vanja Douglas, Kevin R. Kazacos, and Jennifer M. Babik
Author affiliations: University of California, San Francisco, California, USA (C. Langelier, M.J. Reid, C. Halabi, N. Witek, A. LaRiviere, M. Shah, M.R. Wilson, P. Chin-Hong, V. Douglas, J.M. Babik); Purdue University College of Veterinary Medicine, West Lafayette, Indiana, USA (K.R. Kazacos)

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Table 2

Cases of cerebrospinal fluid infection with Baylisascaris spp. roundworms in adults and adolescents, United States and Canada, 1986–2015

Year Patient age, y Location Risk factor(s) Treatment Outcome Reference
1986 21 Oregon, USA Developmental delay and geophagia Not recorded Persistent residual deficits (7)
2000 17 California, USA Developmental delay and geophagia Albendazole and antiinflammatory drugs Died (8)
2007 17 Oregon, USA Altered mentation from drug abuse None Aphasia and memory deficits (9)
2009 54 Missouri, USA Intellectual disability; eating food scraps from public garbage cans None Died (10)
2012 73 British Columbia, Canada Dementia None Identified at time of autopsy (11)
2015 63 California, USA Home or occupational exposure Albendazole (20 mg/kg/d) + dexamethasone (1 mg/kg/d) Partial recovery after 6 weeks This report

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  7. Cunningham  CK, Kazacos  KR, McMillan  JA, Lucas  JA, McAuley  JB, Wozniak  EJ, Diagnosis and management of Baylisascaris procyonis infection in an infant with nonfatal meningoencephalitis. Clin Infect Dis. 1994;18:86872. DOIPubMedGoogle Scholar
  8. Kazacos  KR, Gavin  PJ, Shulman  ST, Tan  TQ, Gerber  SI, Kennedy  WA, Raccoon roundworm encephalitis—Chicago, Illinois, and Los Angeles, California. MMWR Morb Mortal Wkly Rep. 2002;50:11535.
  9. Chun  CS, Kazacos  KR, Glaser  C, Bardo  D, Dangoudoubiyam  S, Nash  R. Global neurologic deficits with baylisascaris encephalitis in a previously healthy teenager. Pediatr Infect Dis J. 2009;28:9257. DOIPubMedGoogle Scholar
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  11. Hung  T, Neafie  RC, Mackenzie  IRA. Baylisascaris procyonis infection in elderly person, British Columbia, Canada. Emerg Infect Dis. 2012;18:3412. DOIPubMedGoogle Scholar
  12. Pai  PJ, Blackburn  BG, Kazacos  KR, Warrier  RP, Bégué  RE. Full recovery from Baylisascaris procyonis eosinophilic meningitis. Emerg Infect Dis. 2007;13:92830. DOIPubMedGoogle Scholar
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  14. Peters  JM, Madhavan  VL, Kazacos  KR, Husson  RN, Dangoudoubiyam  S, Soul  JS. Good outcome with early empiric treatment of neural larva migrans due to Baylisascaris procyonis. Pediatrics. 2012;129:e80611. DOIPubMedGoogle Scholar
  15. Centers for Disease Control and Prevention. Parasites—Baylisascaris infection. Resources for health professionals [cited 2016 Feb 1].

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Page updated: September 12, 2016
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