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Volume 22, Number 8—August 2016

Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014

M. Allison Arwady, Basem M. Alraddadi, Colin Basler, Esam I. Azhar, Eltayb Abuelzein, Abdulfattah I. Sindy, Bakr M. Bin Sadiq, Abdulhakeem O. Althaqafi, Omaima Shabouni, Ayman Banjar, Lia M. Haynes, Susan I. Gerber, Daniel R. Feikin, and Tariq A. MadaniComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.A. Arwady, C. Basler, L.M. Haynes, S.I. Gerber, D.R. Feikin); King Faisal Specialist Hospital and Research Center, Jeddah (B. Alraddadi); Ministry of Health, Jeddah, Saudi Arabia (B. Alraddadi, E.I. Azhar, E. Abuelzein, A.I. Sindy, B.M. Bin Sadiq, A.O. Althaqafi, O. Shabouni, A. Banjar, T.A. Madani); King Abdulaziz University, Jeddah (E.I. Azhar, T.A. Madani); Ministry of National Guard, Jeddah (A.O. Althaqafi)

Main Article

Table 3

Exposures to MERS-CoV index patients by household adult members with and without secondary MERS-CoV infection living in 4 households, Al-Qouz, Saudi Arabia, 2014*

Proximity to index patient
Within 1 m during time he was sick at home 8 (89) 12 (57) 4.0 (0.6–27.8)
Within 1 m every day 7 (78) 9 (43) 3.1 (0.8–12.4)
Within 1 m on day preceding hospitalization 7 (78) 11 (52) 2.3 (0.6–9.3)
Visited index patient in the hospital 6 (67) 10 (48) 1.8 (0.5–5.7)

*Bold indicates statistical significance. This household transmission analysis included relatives >14 y of age living in the 4 households of the index patients, defined as the first patient in the household who received a MERS-CoV diagnosis by rRT-PCR. Secondary transmission is defined as onset of illness or testing positive for MERS-CoV after the household’s index patient had received a diagnosis. Two MERS-CoV–infected household members were excluded from analysis because they had illness onsets before the presumed household index patient’s illness and were subsequently reported to have MERS-CoV antibodies. MERS-CoV, Middle East respiratory syndrome coronavirus; rRT-PCR, real-time reverse transcription PCR.

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Page created: July 15, 2016
Page updated: July 15, 2016
Page reviewed: July 15, 2016
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