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Volume 23, Number 11—November 2017

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Ruvandhi R. Nathavitharana1Comments to Author , Cynthia X. Shi1, Leonid Chindelevitch, Roger Calderon, Zibiao Zhang, Jerome T. Galea, Carmen Contreras, Rosa Yataco, Leonid Lecca, Mercedes C. Becerra, Megan B. Murray, and Ted Cohen
Author affiliations: Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA, and Imperial College London, London, UK (R.R. Nathavitharana); Yale School of Public Health, New Haven, Connecticut, USA (C.X. Shi, T. Cohen); Simon Fraser University, Burnaby, British Columbia, Canada (L. Chindelevitch); Socios En Salud Sucursal Peru, Lima, Peru (R. Calderon, J.T. Galea, C. Contreras, R. Yataco, L. Lecca); Harvard Medical School, Boston (Z. Zhang, J.T. Galea, L. Lecca, M.C. Becerra, M.B. Murray)

Main Article

Table 1

Mycobacterium tuberculosis resistance patterns among patients with pulmonary TB, Lima, Peru, September 2009–August 2012*

Resistance† Simple, 
no. (%) Clonal, 
no. (%) Polyclonal, no. (%)
Pansensitive 1,917 (67.9) 73 (63.5) 88 (54.7)
INH or RIF resistance 260 (9.2) 11 (9.6) 17 (10.6)
Multidrug 333 (11.8) 15 (13.0) 27 (16.8)
312 (11.1)
16 (13.9)
29 (18.0)
Total 2,822 115 161

*Mycobacterium tuberculosis strain type determined by classifier of tandem repeats. INH, isoniazid; RIF, rifampin; TB, tuberculosis.
†Drug susceptibility testing was performed for RIF, INH, streptomycin, ethambutol, and pyrazinamide.

Main Article

1These authors contributed equally to this article.

Page created: October 17, 2017
Page updated: October 17, 2017
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