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Volume 23, Number 11—November 2017
Dispatch

Pulmonary versus Nonpulmonary Nontuberculous Mycobacteria, Ontario, Canada

Sarah K. BrodeComments to Author , Alex Marchand-Austin, Frances B. Jamieson, and Theodore K. Marras
Author affiliations: West Park Healthcare Centre, Toronto, Ontario, Canada (S.K. Brode); University of Toronto, Toronto (S.K. Brode, F.B. Jamieson, T.K. Marras); University Health Network and Sinai Health System, Toronto (S.K. Brode, T.K. Marras); Public Health Ontario, Toronto (A. Marchand-Austin, F.B. Jamieson)

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Figure 1

Prevalence of pulmonary and nonpulmonary nontuberculous mycobacteria (NTM) isolation and pulmonary NTM disease in Ontario, Canada, 1998–2010. Annual increase and modeled annual change were 6.3% (3,4) and 1.04 (95% CI 0.696–1.38)/100,000 population (p<0.001) for pulmonary isolation and 8.0% (3) and 0.402 (95% CI 0.307–0.497)/100,000 population (p<0.001) for pulmonary disease. Significant increases occurred in Mycobacterium avium complex (annual change 0.291 [95% CI 0.236–0.346]/100,000 popu

Figure 1. Prevalence of pulmonary and nonpulmonary nontuberculous mycobacteria (NTM) isolation and pulmonary NTM disease in Ontario, Canada, 1998–2010. Annual increase and modeled annual change were 6.3% (3,4) and 1.04 (95% CI 0.696–1.38)/100,000 population (p<0.001) for pulmonary isolation and 8.0% (3) and 0.402 (95% CI 0.307–0.497)/100,000 population (p<0.001) for pulmonary disease. Significant increases occurred in Mycobacterium avium complex (annual change 0.291 [95% CI 0.236–0.346]/100,000 population; p<0.001); M. xenopi (annual change 0.059 [95% CI 0.015–0.103]/100,000 population; p = 0.002); and M. abscessus (annual change 0.019 [95% CI 0.015–0.024]/100,000 population; p<0.001). TB (all body sites) isolation decreased by an average of 2.2% annually (6.5 to 4.9/100,000 population) during the study period. TB, tuberculosis.

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