Volume 23, Number 11—November 2017
Dispatch
Emergence of Bordetella holmesii as a Causative Agent of Whooping Cough, Barcelona, Spain
Table 2
Comparison of demographic, vaccination-related, clinical characteristics between patients with Bordetella pertussis and B. holmesii infection, Hospital Vall d’Hebron, Barcelona, Spain, 2015–2016*
Characteristic |
B. pertussis, n = 40 |
B. holmesii, n = 10 |
p value |
---|---|---|---|
Median age (range), y | 5.5 (0.08–74) | 9 (4–40) | 0.07 |
Median pertussis vaccine doses received (range) | 4 (0–5) | 5 (3–5) | 0.21 |
Median time from last pertussis vaccine dose received to date of diagnosis (range), y | 1.92 (0.08–11.70) | 3.82 (1.03–14.05) | 0.1 |
Fever, no. (%) | 5 (12.5) | 1 (10) | 1 |
Whoop, no. (%) | 9 (22.5) | 1 (10) | 0.66 |
Paroxysms, no. (%) | 4 (10) | 1 (10) | 1 |
Cough ≥14 d, no. (%) | 12 (30) | 4 (40) | 0.7 |
Hospitalized, no. (%) | 4 (10) | 0 | 0.57 |
*Differences were assessed for significance using the chi-squared exact test (in comparison with independent qualitative variables) and the Mann-Whitney U-test (for quantitative variables; no normality was observed in data distribution). We selected a randomized sample of confirmed B. pertussis cases with a 4:1 relation with B. holmesii–infected patients as a comparison group. p values <0.05 were considered statistically significant at the 95%
CI level.