Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 23, Supplement—December 2017
SUPPLEMENT ISSUE
Global Health Security Supplement
Overview

Contributions of the US Centers for Disease Control and Prevention in Implementing the Global Health Security Agenda in 17 Partner Countries

Arthur G. FitzmauriceComments to Author , Michael Mahar, Leah F. Moriarty, Maureen Bartee, Mitsuaki Hirai, Wenshu Li, A. Russell Gerber, Jordan W. Tappero, Rebecca Bunnell, and GHSA Implementation Group
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 2

Key CDC-supported accomplishments toward achieving GHSA targets related to national laboratory systems in 17 Phase I countries, 2015–2017*

GHSA target and CDC-supported accomplishments
 Related JEE indicators (12)
 No. countries
Real-time biosurveillance with a national laboratory system
Strategic planning and assessment
Identified national policies, legal authorities, and gaps for the conduct of a national public health laboratory system P.1.1, P.1.2, D.1.2, D.1.3, D.1.4 17
Operationalized national plan of action with internationally accepted best practices for priority diseases D.1.1, D.1.2, D.1.3, D.1.4 11
Developed tier-specific testing strategies for priority diseases at designated laboratories D.1.3 10
Specimen referral system
Established functional system for specimen transport to reference laboratories within the appropriate timeframe of collection D.1.2 9
Conducted investigations or training exercises to confirm functionality of specimen referral systems D.1.2 8
Training
Trained laboratory technicians
 D.1.1, D.1.3
 17
Effective modern point-of-care and laboratory-based diagnostics
Strategic planning and assessment
Assessed diagnostics, data quality, and staff performance D.1.1, D.1.3, D.1.4 9
Assessed antimicrobial resistance and drug-resistant tuberculosis laboratory capacity P.3.1 10
Diagnostics
Acquired new diagnostic equipment and capabilities (e.g., specimen test kits) to detect priority pathogens (e.g., influenza virus, poliovirus, HIV, Mycobacterium tuberculosis, Salmonella enterica serovar Typhi, Plasmodium sp., Vibrio cholerae)
 D.1.1, D.1.3
 16
Whole-of-government national biosafety and biosecurity system is in place, ensuring that especially dangerous pathogens are identified, held, secured, and monitored in a minimal number of facilities according to best practices; biologic risk management training and educational outreach are conducted to promote a shared culture of responsibility, reduce dual-use risks, mitigate biologic proliferation and deliberate use threats, and ensure safe transfer of biologic agents; and country-specific biosafety and biosecurity legislation, laboratory licensing, and pathogen control measures are in place as appropriate
Biosafety and biosecurity
Trained staff on biosafety and biosecurity P.6.2 15
Identified staff in ministries of health, agriculture, and defense responsible for inspection or certification of laboratories for compliance with biosafety and biosecurity requirements P.6.1 8
Inventoried dangerous pathogens and developed a plan to manage them P.6.1 6

*Countries: Bangladesh, Burkina Faso, Cameroon, Côte d’Ivoire, Ethiopia, Guinea, India, Indonesia, Kenya, Liberia, Mali, Pakistan, Senegal, Sierra Leone, Tanzania, Uganda, and Vietnam. CDC, US Centers for Disease Control and Prevention; GHSA, Global Health Security Agenda; JEE, Joint External Evaluation tool.

Main Article

References
  1. World Health Organization. Report of the Review Committee on the Role of the International Health Regulations (2005) in the Ebola Outbreak and Response [cited 2017 Aug 2]. http://www.who.int/ihr/review-committee-2016
  2. World Health Organization. Report of the Review Committee on the Functioning of the International Health Regulations (2005) in Relation to Pandemic (H1N1) 2009 [cited 2017 Aug 2]. http://www.who.int/ihr/publications/RC_report
  3. Jonas  O. Pandemic risk. Background paper for the World Development Report [cited 2017 Aug 2]. http://siteresources.worldbank.org/EXTNWDR2013/Resources/8258024-1352909193861/8936935-1356011448215/8986901-1380568255405/WDR14_bp_Pandemic_Risk_Jonas.pdf
  4. Katz  R, Sorrell  EM, Kornblet  SA, Fischer  JE. Global Health Security Agenda and the International Health Regulations: moving forward. Biosecur Bioterror. 2014;12:231–8. DOIPubMedGoogle Scholar
  5. Global Health Security Agenda. [cited 2017 Apr 27]. https://www.GHSAgenda.org
  6. Centers for Disease Control and Prevention. US Commitment to the Global Health Security Agenda [cited 2017 Apr 27]. https://www.cdc.gov/globalhealth/security/pdf/ghs_us_commitment.pdf
  7. Schuchat  A, Tappero  J, Blandford  J. Global health and the US Centers for Disease Control and Prevention. Lancet. 2014;384:98–101. DOIPubMedGoogle Scholar
  8. Centers for Disease Control and Prevention. Global Health Security Agenda: action packages [cited 2017 Aug 2]. https://www.cdc.gov/globalhealth/security/actionpackages/default.htm
  9. World Health Organization. International Health Regulations (2005). 3rd ed. [cited 2017 Aug 2]. http://apps.who.int/iris/ bitstream/10665/246107/1/9789241580496-eng.pdf
  10. Borchert  JN, Tappero  JW, Downing  R, Shoemaker  T, Behumbiize  P, Aceng  J, et al.; Centers for Disease Control and Prevention (CDC). Rapidly building global health security capacity—Uganda demonstration project, 2013. MMWR Morb Mortal Wkly Rep. 2014;63:73–6.PubMedGoogle Scholar
  11. Tran  PD, Vu  LN, Nguyen  HT, Phan  LT, Lowe  W, McConnell  MS, et al.; Centers for Disease Control and Prevention (CDC). Strengthening global health security capacity—Vietnam demonstration project, 2013. MMWR Morb Mortal Wkly Rep. 2014;63:77–80.PubMedGoogle Scholar
  12. World Health Organization. Joint External Evaluation tool: International Health Regulations (2005) [cited 2017 Aug 2]. http://apps.who.int/iris/handle/10665/204368
  13. Balajee  SA, Arthur  R, Mounts  AW. Global health security: building capacities for early event detection, epidemiologic workforce, and laboratory response. Health Secur. 2016;14:424–32. DOIPubMedGoogle Scholar
  14. Centers for Disease Control and Prevention. Field Epidemiology Training Program: how we train [cited 2017 Apr 27]. https://www.cdc.gov/globalhealth/healthprotection/fetp/train.html
  15. Ameme  DK, Nyarko  KM, Kenu  E, Afari  EA. Strengthening surveillance and response to public health emergencies in the West African sub-region: the role of Ghana FELTP. Pan Afr Med J. 2016;25(Suppl 1).
  16. Andre  A, Lopez  A, Perkins  S, Lambert  S, Chace  L, Noudek  N, et al. Frontline field epidemiology training programs as a strategy to improve disease surveillance and response. Emerg Infect Dis. 2017;23:166. DOIPubMedGoogle Scholar
  17. Centers for Disease Control and Prevention. CDC Emergency Operations Center: Public Health Emergency Management Fellowship [cited 2017 Apr 27]. https://www.cdc.gov/phpr/eoc/emergencymanagementfellowship.htm
  18. American Veterinary Medical Association. One Health: a new professional imperative. One Health Initiative Task Force Final Report. Schaumburg (IL): The Association; 2008 [cited 2017 Aug 2]. https://www.avma.org/KB/Resources/Reports/Pages/One-Health.aspx
  19. Fasina  FO, Shittu  A, Lazarus  D, Tomori  O, Simonsen  L, Viboud  C, et al. Transmission dynamics and control of Ebola virus disease outbreak in Nigeria, July to September 2014. Euro Surveill. 2014;19:20920. DOIPubMedGoogle Scholar
  20. Kekulé  AS. Learning from Ebola virus: how to prevent future epidemics. Viruses. 2015;7:3789–97. DOIPubMedGoogle Scholar
  21. Smolinski  MS, Crawley  AW, Olsen  JM. Finding outbreaks faster. Health Secur. 2017;15:215–20. DOIPubMedGoogle Scholar
  22. Baize  S, Pannetier  D, Oestereich  L, Rieger  T, Koivogui  L, Magassouba  N, et al. Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med. 2014;371:1418–25. DOIPubMedGoogle Scholar
  23. Maïnassara  HB, Paireau  J, Idi  I, Pelat  J-PM, Oukem-Boyer  OOM, Fontanet  A, et al. Response strategies against meningitis epidemics after elimination of serogroup A meningococci, Niger. Emerg Infect Dis. 2015;21:1322–9. DOIPubMedGoogle Scholar
  24. Dowell  SF, Blazes  D, Desmond-Hellmann  S. Four steps to precision public health. Nature. 2016;540:189–91. DOIGoogle Scholar
  25. Sealy  TK, Erickson  BR, Taboy  CH, Ströher  U, Towner  JS, Andrews  SE, et al. Laboratory Response to Ebola - West Africa and United States. MMWR Suppl. 2016;65:44–9. DOIPubMedGoogle Scholar
  26. Olmsted  SS, Moore  M, Meili  RC, Duber  HC, Wasserman  J, Sama  P, et al. Strengthening laboratory systems in resource-limited settings. Am J Clin Pathol. 2010;134:374–80. DOIPubMedGoogle Scholar
  27. Wolicki  SB, Nuzzo  JB, Blazes  DL, Pitts  DL, Iskander  JK, Tappero  JW. Public health surveillance: at the core of the Global Health Security Agenda. Health Secur. 2016;14:185–8. DOIPubMedGoogle Scholar
  28. Kim  HS. Korea dedicates $100 million to help poor countries fight infectious disease [cited 2017 Aug 2]. http://www.koreatimesus.com/s-korea-dedicates-100-million-to-help-poor-countries-fight-infectious-diseases
  29. GHSA standardized milestone library [cited 2017 Oct 6]. https://www.ghsagenda.org/docs/default-source/default-document-library/GHSA-Milestone-Library.pdf
  30. The World Bank. Transcript: World Bank Group opening press conference by President Jim Yong Kim at the 2017 WBG/IMF Spring Meetings. Washington: World Bank; 2017 [cited 2017 Aug 2]. http://www.worldbank.org/en/news/speech/2017/04/20/2017-wbgimf-spring-meetings-world-bank-group-opening-press-conference-by-president-jim-yong-kim
  31. Gostin  LO, Ayala  AS. Global health security in an era of explosive pandemic potential. Journal of National Security Law and Policy. 2017;9:1.
  32. Sands  P, El Turabi  A, Saynisch  PA, Dzau  VJ. Assessment of economic vulnerability to infectious disease crises. Lancet. 2016;388:2443–8. DOIPubMedGoogle Scholar

Main Article

1Members of this group are listed at the end of this article.

Page created: November 29, 2017
Page updated: November 29, 2017
Page reviewed: November 29, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external