Volume 23, Number 2—February 2017
Research Letter
Outbreak of Legionnaire’s Disease Caused by Legionella pneumophila Serogroups 1 and 13
Toshiro Kuroki1
, Junko Amemura-Maekawa1, Hitomi Ohya, Ichiro Furukawa, Miyuki Suzuki, Tomoka Masaoka, Kastuhiro Aikawa, Kazumi Hibi, Masatomo Morita, Ken-Ichi Lee, Makoto Ohnishi, and Fumiaki Kura
, Junko Amemura-Maekawa1, Hitomi Ohya, Ichiro Furukawa, Miyuki Suzuki, Tomoka Masaoka, Kastuhiro Aikawa, Kazumi Hibi, Masatomo Morita, Ken-Ichi Lee, Makoto Ohnishi, and Fumiaki Kura
Table
Genetic characteristics of Legionella pneumophila isolates from patients with pneumonia and from environmental samples, Japan, 2015*
| Serogroup | PGFE profile† | ST‡ | ST profile, flaA, pilE, asd, mip, mompS, proA, neuA | Sample source | cgMLST profile§ |
|---|---|---|---|---|---|
| 1 | A | ST2114 | 6, 10, 21, 3, 17, 14, 9 | Patients 1, 7 | a, b |
| Bath 1 (bath water)¶ | b | ||||
| Bath 2 (spout swab) |
b |
||||
| 1 |
A |
ST2121 |
6, 10, 21, 3, 17, 14, 57 |
Bath 1 (bath water)¶ |
a |
| 1 | B | ST2114 | 6, 10, 21, 3, 17, 14, 9 | Patients 2, 5, 7 | b, b, b |
| Bath 1(bathtub swab) | b | ||||
| Bath 2 (bath water)¶ |
b |
||||
| 1 |
C |
ST1447 |
6, 10, 20, 13, 9, 4, 11 |
Bath 3 (hair trap debris) |
c |
| 13 | B | ST2113 | 6, 10, 21, 10, 17, 14, 209 | Patient 2 | d |
| Bath 1 (bath water)¶ | d | ||||
| Bath 2 (bath water)¶ | Not done | ||||
| Bath 2 (spout swab) |
d |
||||
| 10 | D | ST2115 | 7, 10, 17, 3, 13, 14, 207 | Bath 4 (spout swab) | e |
| Bath 5 (bathtub swab) | f |
*cgMLST, core genome multilocus sequence typing; PFGE, pulsed-field gel electrophoresis; ST, sequence type.
†Profiles A and B were obtained from clinical and environmental samples. Profiles C and D were obtained from environmental samples only.
‡New STs from this study were assigned ST2113, ST2114, ST2115, and ST2121.
§Each profile letter indicates a tentative cgMLST profile of 1 strain.
¶Concentrations of L. pneumophila in bath water were 800 CFU/L in bath 1, and 1,100 CFU/L in bath 2.
1These authors contributed equally to this article.
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