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Volume 23, Number 2—February 2017
Dispatch

Low Circulation of Zika Virus, Cambodia, 2007–2016

Veasna Duong, Sivuth Ong, Rithea Leang, Rekol Huy, Sowath Ly, Ugo Mounier, Teyputita Ou, Saraden In, Borin Peng, Sreymom Ken, Philippe Buchy, Arnaud Tarantola, Paul F. Horwood, and Philippe DussartComments to Author 
Author affiliations: Institut Pasteur, Phnom Penh, Cambodia (V. Duong, S. Ong, S. Ly, U. Mounier, T. Ou, S. In, B. Peng, S. Ken, A. Tarantola, P.F. Horwood, P. Dussart); National Center for Parasitology, Entomology, and Malaria Control, Phnom Penh (R. Leang, R. Huy); GlaxoSmithKline Vaccines Research and Development, Singapore (P. Buchy)

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Figure 2

Geographic distribution of Zika virus in Cambodia. PCR- and IgM-positive cases were from 9 different provinces in north, central and south Cambodia. The 5 Zika virus–positive samples by quantitative real-time reverse transcription (qRT-PCR) in this study were distributed as follows: the 2007 (n = 1) sample was received from Kampong Cham province, and the other cases from 2008 (n = 1), 2009 (n = 2), and 2015 (n = 1) were from the Phnom Penh area (red star). The first case of Zika virus infection

Figure 2. Geographic distribution of Zika virus in Cambodia. PCR- and IgM-positive cases were from 9 different provinces in north, central and south Cambodia. The 5 Zika virus–positive samples by quantitative real-time reverse transcription (qRT-PCR) in this study were distributed as follows: the 2007 (n = 1) sample was received from Kampong Cham province, and the other cases from 2008 (n = 1), 2009 (n = 2), and 2015 (n = 1) were from the Phnom Penh area (red star). The first case of Zika virus infection previously reported in Cambodia by conventional RT-PCR was diagnosed in a patient from Kampong Speu province (9). The 16 additional serum samples found to be positive for Zika virus IgM were, from oldest to the most recent, from Phnom Penh (2007, n = 1; 2008, n = 1; 2010, n = 2); Battambang (2007, n = 1; 2012, n = 1); Takeo (2012, n = 1); Kampong Speu (2012, n = 1); Kampot (2012, n = 1; 2015, n = 1); Kampong Chhnang (2015, n = 1); Banteay Meanchey (2015, n = 1); and Siem Reap (2015, n = 4) provinces. Light gray indicates provinces with IgM-positive cases, dark gray indicates province with PCR-positive cases, and black indicates provinces with PCR-positive and IgM-positive cases. Inset shows location of Cambodia in Southeast Asia.

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