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Volume 23, Number 3—March 2017

Molecular, Spatial, and Field Epidemiology Suggesting TB Transmission in Community, Not Hospital, Gaborone, Botswana

Diya SurieComments to Author , Othusitse Fane, Alyssa Finlay, Matsiri Ogopotse, James L. Tobias, Eleanor S. Click, Chawangwa Modongo, Nicola M. Zetola, Patrick K. Moonan, John E. Oeltmann, and for the Kopanyo Study Group
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D. Surie, A. Finlay, E.S. Click, P.K. Moonan, J.E. Oeltmann); Botswana-UPenn Partnership, Gaborone, Botswana (O. Fane, M. Ogopotse, C. Modongo, N.M. Zetola); Centers for Disease Control and Prevention, Gaborone (A. Finlay); Northrop Grumman, Atlanta, (J.L. Tobias)

Main Article

Table 1

Patient and disease characteristics in a tuberculosis cluster, Gaborone, Botswana, 2012–2015

Characteristic No. (%)*
M 14 (58)
F 10 (42)
Age, median y (range) 31 (15–55)
Primary residence in Gaborone 20 (83)
Alcohol use 4 (17)
Tobacco use 3 (13)
Cough 23 (96)
History of visit to the hospital 10 (42)
1 (4)
Pulmonary 24 (100)
Extrapulmonary involvement† 2 (8)
Positive sputum smear at diagnosis 12 (75)‡
HIV infection 16 (67)
CD4 cells/mL, median (range)§ 310 (14–700)
Receiving antiretroviral therapy at time of tuberculosis diagnosis 9 (56)

*Data are no. (%) for 24 patients except as indicated.
†In addition to pulmonary tuberculosis, 2 patients also had extrapulmonary involvement (pleural and abdominal tuberculosis).
‡Sixteen patients had a sputum smear tested at diagnosis.
§CD4 counts were available for 11 of 16 patients with HIV infection.

Main Article

1Other members of the Kopanyo Study Group are listed at the end of this article.

Page created: February 17, 2017
Page updated: February 17, 2017
Page reviewed: February 17, 2017
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