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Volume 23, Number 3—March 2017
Research

Mycobacterium tuberculosis Transmission among Elderly Persons, Yamagata Prefecture, Japan, 2009–2015

Junji SetoComments to Author , Takayuki Wada, Yu Suzuki, Tatsuya Ikeda, Katsumi Mizuta, Taro Yamamoto, and Tadayuki Ahiko
Author affiliations: Yamagata Prefectural Institute of Public Health, Yamagata, Japan (J. Seto, Y. Suzuki, T. Ikeda, K. Mizuta, T. Ahiko); Nagasaki University, Nagasaki, Japan (T. Wada, T. Yamamoto)

Main Article

Table 2

Odds ratio for cluster formation among 494 persons with tuberculosis, Yamagata Prefecture, Japan, 2009–2015*

Patient characteristic 24Beijing-VNTR profile, no. (%)
Odds ratio (95% CI)†
Not clustered, n = 366 Clustered, n = 128 Univariate Multivariate‡
Age group
<39 31 (8.5) 30 (23.4) 1.0 1.0
40–59 25 (6.8) 21 (16.4) 0.9 (0.4–1.9) 0.8 (0.3–1.8)
60–79 96 (26.2) 35 (27.3) 0.4 (0.2–0.7) 0.4 (0.2–0.8)
>80
214 (58.5)
42 (32.8)

0.2 (0.1–0.4)
0.2 (0.1–0.4)
Sex
F 143 (39.1) 59 (46.1) 1.3 (0.9–2.0) 1.6 (0.99–2.4)
M
223 (60.9)
69 (53.9)

1.0
1.0
Birthplace
Japan 351 (95.9) 127 (99.2) 5.4 (0.7–41.5) 16.7 (2.0–137.0)
Other
15 (4.1)
1 (0.8)

1.0
1.0
Site of disease
Pulmonary, sputum smear–positive 251 (68.6) 78 (60.9) 1.0
Pulmonary, sputum smear–negative 97 (26.5) 44 (34.4) 1.5 (0.9–2.3)
Extrapulmonary
18 (4.9)
6 (4.7)

1.1 (0.4–2.8)

Treatment history
Initial 343 (93.7) 123 (96.1) 1.6 (0.6–4.4)
Retreatment
23 (6.3)
5 (3.9)

1.0

M. tuberculosis lineage
Non-Beijing 102 (27.9) 38 (29.7) 0.7 (0.4–1.4) 1.2 (0.6–2.3)
ST11/26 14 (3.8) 19 (14.8) 2.7 (1.2–6.3) 2.5 (1.02–6.1)
STK 72 (19.7) 10 (7.8) 0.3 (0.1–0.6) 0.4 (0.2–1.1)
ST3 68 (18.6) 15 (11.7) 0.4 (0.2–0.9) 0.8 (0.3–1.7)
ST25/19 60 (16.4) 21 (16.4) 0.7 (0.4–1.4) 1.0 (0.5–2.2)
Modern Beijing 50 (13.7) 25 (19.5) 1.0 1.0

*–, no variables.
†CIs that do not overlap the null value of odds ratio = 1 are shown in bold.
‡Adjusted for the other factors used in the multivariate model.

Main Article

Page created: February 17, 2017
Page updated: February 17, 2017
Page reviewed: February 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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