Volume 23, Number 3—March 2017
Research
Comparison of Sputum-Culture Conversion for Mycobacterium bovis and M. tuberculosis
Table 1
Variable | Cause of tuberculosis |
p value† | |
---|---|---|---|
M. bovis, n = 297 | M. tuberculosis, n = 30,848 | ||
Age, y | |||
0–4 | 0 | 18 (0.1) | 0.52 |
5–14 | 2 (0.7) | 202 (0.7) | |
15–24 | 46 (15.5) | 3966 (12.9) | |
25–44 | 105 (35.4) | 10,553 (34.2) | |
45–64 | 99 (33.3) | 10,237 (33.2) | |
>65 | 45 (15.2) | 5872 (19.0) | |
Median age, y (interquartile range) | 43 (29–56) | 46 (30–60) | 0.12 |
Sex | |||
M | 174 (58.6) | 20,303 (65.8) | 0.01 |
F | 123 (41.4) | 10,536 (34.2) | |
Race/ethnicity | |||
White, non-Hispanic | 9 (3.0) | 5205 (16.8) | <0.0001 |
Native American, non-Hispanic | 0 | 456 (1.5) | |
Asian, non-Hispanic | 3 (1.0) | 7869 (26.0) | |
Black, non-Hispanic | 8 (2.7) | 7578 (25.0) | |
Hispanic | 276 (93.2) | 9177 (30.3) | |
Country of birth | |||
United States | 41 (13.8) | 12,442 (40.3) | <0.0001 |
Other‡ | 256 (86.2) | 18,371 (59.5) | |
Reported HIV status§ | |||
Positive | 17 (5.7) | 1851 (6.0) | <0.0001 |
Negative | 166 (55.9) | 21,585 (70.0) | |
Unknown | 114 (38.4) | 7412 (24.0) | |
Clinical presentation at diagnosis | |||
Pulmonary disease | 193 (65.0) | 27,757 (90.0) | <0.0001 |
Pulmonary and extrapulmonary disease | 104 (35.0) | 3090 (10.0) | |
Computed tomography or other chest imaging findings¶ | |||
Cavitary disease | 90/193 (46.6) | 12,476/27,757 (45.0) | 0.64 |
Noncavitary disease | 103/193 (53.4) | 15,281/27,757 (55.0) | |
Sputum smear result | |||
Positive | 189 (63.6) | 20,744 (67.3) | 0.40 |
Negative | 98 (33.0) | 9403 (30.5) | |
Not obtained | 10 (3.4) | 689 (2.2) | |
Bacillary burden# | |||
High | 84 (28.3) | 11,154 (36.2) | 0.03 |
Medium | 120 (40.4) | 11,445 (37.1) | |
Low | 85 (28.6) | 7734 (25.1) | |
Unknown | 8 (2.7) | 515 (1.7) | |
Treatment outcome** | |||
Completed | 235 (83.9) | 25,535 (90.5) | 0.001 |
Died | 25 (8.9) | 1447 (5.1) | |
Other†† | 20 (7.4) | 1238 (4.4) |
*Values are no. (%) unless otherwise indicated. Sums of counts across categories for a specific factor might be less than total counts in the column headings because of missing or incomplete data.
†Determined by using Pearson χ2 test unless otherwise indicated.
‡Restricted to foreign-born persons.
§HIV status data are unknown for patients reported for California and Vermont during 2006–2011. Unknown also includes data from other states reporting unknown HIV status for tuberculosis patients.
¶Cavitary status was documented if reports of either conventional radiography or computed tomography indicated its presence.
#A bacillary burden composite variable was created by using smear status and radiographic evidence of cavitation.
**Outcome data are available for, and restricted to, patients reported during 2006–2013.
††Includes treatment stopped because of adverse events; patients were lost to follow-up, moved, refused treatment; and unknown reasons.