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Volume 23, Number 8—August 2017
Dispatch

Occupational Exposures to Ebola Virus in Ebola Treatment Center, Conakry, Guinea

Hélène SaviniComments to Author , Frédéric Janvier, Ludovic Karkowski, Magali Billhot, Marc Aletti, Julien Bordes, Fassou Koulibaly, Pierre-Yves Cordier, Jean-Marie Cournac, Nancy Maugey, Nicolas Gagnon, Jean Cotte, Audrey Cambon, Christine Mac Nab, Sophie Moroge, Claire Rousseau, Vincent Foissaud, Thierry De Greslan, Hervé Granier, Gilles Cellarier, Eric Valade, Philippe Kraemer, Philippe Alla, Audrey Mérens, Emmanuel Sagui, Thierry Carmoi, and Christophe Rapp
Author affiliations: French Military Teaching Hospital Laveran, Marseille, France (H. Savini, P.-Y. Cordier, S. Moroge, P. Kraemer, E. Sagui); French Military Teaching Hospital Saint Anne, Toulon, France (F. Janvier, J. Bordes, J. Cotte, G. Cellarier, P. Alla); French Military Teaching Hospital Legouest, Metz, France (L. Karkowski, N. Gagnon); French Military Teaching Hospital Val de Grâce, Paris, France (M. Billhot, A. Cambon, T. De Greslan, T. Carmoi); French Military Teaching Hospital Percy, Clamart, France (M. Aletti, J.-M. Cournac, C. Mac Nab, V. Foissaud); Guinean Military Health Services, Conakry, Guinea (F. Koulibaly); Frégate Européenne Multi-Mission Aquitaine, Bordeaux Consortium for Regenerative Medicine, Brest, France (N. Maugey); French Military Teaching Hospital Clermont Tonnerre, Brest, France (C. Rousseau, H. Granier); Institut de Recherche Biomédicale des Armées, Brétigny sur Orge, France (E. Valade); French Military Teaching Hospital Bégin, Saint Mandé, France (A. Mérens, C. Rapp)

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Table 1

Risk levels of transmission factors for Ebola virus disease for healthcare workers, Conakry, Guinea*

Exposure Risk level
EVD with diarrhea, vomiting, and hemorrhaging EVD without diarrhea, vomiting, and hemorrhaging
Contact (>1 m) with patients not projecting biological fluids Low Low
Close contact (<1 m) with patients not projecting biological fluids Low High
Direct contact with biological fluids High High
Cumulative incidents during removal of PPE Low High
Transcutaneous or mucosal exposure to infected biological fluids Maximum Maximum

*Adapted from recommendations of the French High Council on Public Health (5). EVD, Ebola virus disease; PPE, personal protective equipment.

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References
  1. World Health Organization. Health workers Ebola infections in Guinea, Liberia, and Sierra Leone. A preliminary report [cited 2015 May 21]. http://apps.who.int/iris/bitstream/10665/171823/1/WHO_EVD_SDS_REPORT_2015.1_eng.pdf
  2. Lopaz  MA, Amela  C, Ordobas  M, Dominguez-Berjon  MF, Alvarez  C, Martinez  M, et al. Working group of Ebola outbreak investigation team of Madrid. Euro Surveill. 2015;20:21003.PubMed
  3. Liddell  AM, Davey  RT Jr, Mehta  AK, Varkey  JB, Kraft  CS, Tseggay  GK, et al. Characteristics and clinical management of a cluster of 3 patients with Ebola virus disease, including the first domestically acquired cases in the United States. Ann Intern Med. 2015;163:8190. DOIPubMed
  4. Zellmer  C, Van Hoof  S, Safdar  N. Variation in health care worker removal of personal protective equipment. Am J Infect Control. 2015;43:7501. DOIPubMed
  5. French High Council on Public Health. Advice relative to the management of an occupational exposure from a patient with suspected of proven Ebola viral disease [in French] [cited 2014 Dec 4]. http://www.hscp.fr
  6. Mulligan  MJ, Siebert  PN. Era of global Ebola: risk of exposure in health-care workers. Lancet Infect Dis. 2015;15:12489. DOIPubMed
  7. Grinnell  M, Dixon  MG, Patton  M, Fitter  D, Bilivogui  P, Johnson  C, et al. Ebola virus disease in health care workers—Guinea, 2014. MMWR Morb Mortal Wkly Rep. 2015;64:10837. DOIPubMed
  8. Olu  O, Kargbo  B, Kamara  S, Wurie  AH, Amone  J, Ganda  L, et al. Epidemiology of Ebola virus disease transmission among health care workers in Sierra Leone, May to December 2014: a retrospective descriptive study. BMC Infect Dis. 2015;15:416. DOIPubMed
  9. Forrester  JD, Hunter  JC, Pillai  SK, Arwady  MA, Ayscue  P, Matanock  A, et al.; Centers for Disease Control and Prevention (CDC). Cluster of Ebola cases among Liberian and U.S. health care workers in an Ebola treatment unit and adjacent hospital — Liberia, 2014. MMWR Morb Mortal Wkly Rep. 2014;63:9259.PubMed
  10. Tarantola  A, Golliot  F, Astagneau  P, Fleury  L, Brücker  G, Bouvet  E; CCLIN Paris-Nord Blood and Body Fluids (BBF) Exposure Surveillance Taskforce. Occupational blood and body fluids exposures in health care workers: four-year surveillance from the Northern France network. Am J Infect Control. 2003;31:35763. DOIPubMed
  11. Youkee  D, Brown  CS, Lilburn  P, Shetty  N, Brooks  T, Simpson  A, et al. Assessment of environmental contamination and environmental decontamination practices within an Ebola holding unit, Freetown, Sierra Leone. PLoS One. 2015;10:e0145167. DOIPubMed
  12. Smither  SJ, Eastaugh  LS, Steward  JA, Nelson  M, Lenk  RP, Lever  MS. Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antiviral Res. 2014;104:1535. DOIPubMed
  13. Van Herp  M, Declerck  H, Decroo  T. Favipiravir—a prophylactic treatment for Ebola contacts? Lancet. 2015;385:2350. DOIPubMed
  14. Jacobs  M, Aarons  E, Bhagani  S, Buchanan  R, Cropley  I, Hopkins  S, et al. Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers. Lancet Infect Dis. 2015;15:13004. DOIPubMed
  15. Grélot  L, Koulibaly  F, Maugey  N, Janvier  F, Foissaud  V, Aletti  M, et al. Moderate thermal strain in healthcare workers wearing personal protective equipment during treatment and care activities in the context of the 2014 Ebola virus disease outbreak. J Infect Dis. 2015.PubMed

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