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Volume 23, Number 8—August 2017

Dispatch

Genesis of Influenza A(H5N8) Viruses

Rabeh El-Shesheny, Subrata Barman, Mohammed M. Feeroz, M. Kamrul Hasan, Lisa Jones-Engel, John Franks, Jasmine Turner, Patrick Seiler, David Walker, Kimberly Friedman, Lisa Kercher, Sajeda Begum, Sharmin Akhtar, Ashis Kumar Datta, Scott Krauss, Ghazi Kayali, Pamela McKenzie, Richard J. Webby, and Robert G. WebsterComments to Author 
Author affiliations: National Research Centre, Giza, Egypt (R. El-Shesheny); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R. El-Shesheny, S. Barman, J. Franks, J. Turner, P. Seiler, D. Walker, K. Friedman, L. Kercher, S. Krauss, P. McKenzie, R.J. Webby, R.G. Webster); Jahangirnagar University, Savar, Dhaka, Bangladesh (M.M. Feeroz, M.K. Hasan, S. Begum, S. Akhtar, A.K. Datta); University of Washington, Seattle, Washington, USA (L. Jones-Engel); University of Texas Health Sciences Center, Houston, Texas, USA (G. Kayali); Human Link, Hazmieh, Lebanon (G. Kayali)

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Table

Nucleotide identity of novel HPAI A(H5N8) clade 2.3.4.4 virus and viruses isolated from Tanguar haor, Bangladesh*

Gene and genotype, novel HPAI A(H5N8) clade 2.3.4.4, 2016 Viruses from Tanguar haor (Central Asian flyway)† % Identity
PB2
Genotype 1‡ A/duck/Bangladesh/24705/2015(H7N1)§ 98.4–98.6
Genotype 2‡
A/duck/Bangladesh/26920/2015(H3N6)
98.7–98.9
PB1
A/duck/Bangladesh/26918/2015(H3N6)
97.3–98
PA
Genotype 1‡ A/duck/Bangladesh/24706/2015(H7N1) 95.3
Genotype 2‡
A/duck/Bangladesh/26918/2015(H3N6)
97.1–97.3
NP
Genotype 1‡ A/duck/Bangladesh/26992/2015(H7N9) 98.6
Genotype 2‡
A/duck/Bangladesh/24706/2015(H7N1)
97–97.1
M A/duck/Bangladesh/24704/2015(H15N9) 98–98.5

*HPAI, highly pathogenic avian influenza; NP, nucleoprotein; M, matrix; PA, polymerase acidic; PB, polymerase basic.
†All Eurasian low-pathogenicity avian influenza lineage.
‡Genotype 1 viruses isolated from Siberia; genotype 2 viruses isolated from Europe.
§Selected 1 representative virus isolate from the Tanguar haor region of Bangladesh.

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