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Volume 24, Number 1—January 2018

Sensitivity and Specificity of Suspected Case Definition Used during West Africa Ebola Epidemic

Christopher H. HsuComments to Author , Steven W. Champaloux, Sakoba Keïta, Lise Martel, Pepe Bilivogui, Barbara Knust, and Andrea M. McCollum
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.H. Hsu, S.W. Champaloux, L. Martel, B. Knust, A.M. McCollum); Prevention and Disease Control, Conakry, Guinea (S. Keïta); Surveillance of National Ebola Coordination Cell, Conakry (P. Bilivogui)

Main Article

Table 3

Analysis of Ebola virus disease suspected case definition during West Africa Ebola epidemic, Guinea, March–October 2014

Component of case definition analyzed p value Sensitivity, % Specificity, % Positive predictive value, % Negative predictive value, %
Complete definition <0.0001 68.9 49.6 64.2 54.9
Epidemiologic risk criteria* <0.0001 74.7 67.1 82.3 56.4
Clinical criteria <0.0001 57.2 62.0 66.4 52.5
Unexplained bleeding 0.04 9.9 86.6 49.1 42.3
Unexplained death <0.0001 14.2 92.8 72.0 45.2

*Contact with infected persons or body fluid, handling of bushmeat, attending the funeral of an Ebola case-patient.

Main Article

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
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