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Volume 24, Number 1—January 2018
Research

Sensitivity and Specificity of Suspected Case Definition Used during West Africa Ebola Epidemic

Christopher H. HsuComments to Author , Steven W. Champaloux, Sakoba Keïta, Lise Martel, Pepe Bilivogui, Barbara Knust, and Andrea M. McCollum
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.H. Hsu, S.W. Champaloux, L. Martel, B. Knust, A.M. McCollum); Prevention and Disease Control, Conakry, Guinea (S. Keïta); Surveillance of National Ebola Coordination Cell, Conakry (P. Bilivogui)

Main Article

Table 3

Analysis of Ebola virus disease suspected case definition during West Africa Ebola epidemic, Guinea, March–October 2014

Component of case definition analyzed p value Sensitivity, % Specificity, % Positive predictive value, % Negative predictive value, %
Complete definition <0.0001 68.9 49.6 64.2 54.9
Epidemiologic risk criteria* <0.0001 74.7 67.1 82.3 56.4
Clinical criteria <0.0001 57.2 62.0 66.4 52.5
Unexplained bleeding 0.04 9.9 86.6 49.1 42.3
Unexplained death <0.0001 14.2 92.8 72.0 45.2

*Contact with infected persons or body fluid, handling of bushmeat, attending the funeral of an Ebola case-patient.

Main Article

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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