Volume 24, Number 11—November 2018
Research
Norovirus Gastroenteritis among Hospitalized Patients, Germany, 2007–2012
Table 3
Country | Data source | Study years | Infection type or diagnostic position | No. cases/10,000 population |
---|---|---|---|---|
Germany (this study) |
Retrospective analysis of DESTATIS hospitalization data |
2007–2012 | Primary diagnosis | 3.4 |
2007–2012 |
Secondary diagnosis |
4.9 |
||
Germany (14) |
Retrospective analysis of RKI notification data |
2002–2008 |
Nosocomial |
1.6 |
Germany (13) |
Retrospective analysis of RKI notification data |
2001–2009 |
Community-acquired |
1.0–2.5 |
England (26) |
Retrospective regression analysis using PHE notification data and HES emergency admissions |
2000–2006 | Community-acquired | 1.0–4.3† |
2000–2006 |
Community-acquired |
0.23–0.48‡ |
||
England (27) |
Retrospective analysis of GP and hospital discharge databases |
2007–2013 |
Any position |
6.2–8.0 |
The Netherlands (23) |
Retrospective analysis of national surveillance data |
2009 |
Community-acquired |
1.2 |
United States (24) |
Retrospective regression analysis using NIS data |
1996–2007 |
Any position |
2.1 |
Canada (25) | Retrospective binomial generalized linear analysis using CIHI-HMDB data | 2006–2011 | Primary diagnosis | 0.05 |
2006–2011 | Other diagnosis | 0.17 |
*CIHI-HMDB, Canadian Institutes of Health Information–Hospital Morbidity Database; DESTATIS, German Federal Statistics Office; HES, Hospital Episode Statistics; NIS, Nationwide Inpatient Sample; PHE, Public Health England; RKI, Robert Koch Institute.
†Age >65 y.
‡Age 18–64 y.
References
- Lopman BA, Steele D, Kirkwood CD, Parashar UD. The vast and varied global burden of norovirus: prospects for prevention and control. PLoS Med. 2016;13:e1001999. DOIPubMedGoogle Scholar
- Hemming M, Räsänen S, Huhti L, Paloniemi M, Salminen M, Vesikari T. Major reduction of rotavirus, but not norovirus, gastroenteritis in children seen in hospital after the introduction of RotaTeq vaccine into the National Immunization Programme in Finland. Eur J Pediatr. 2013;172:739–46. DOIPubMedGoogle Scholar
- Bucardo F, Reyes Y, Svensson L, Nordgren J. Predominance of norovirus and sapovirus in Nicaragua after implementation of universal rotavirus vaccination. PLoS One. 2014;9:e98201. DOIPubMedGoogle Scholar
- Payne DC, Vinjé J, Szilagyi PG, Edwards KM, Staat MA, Weinberg GA, et al. Norovirus and medically attended gastroenteritis in U.S. children. N Engl J Med. 2013;368:1121–30. DOIPubMedGoogle Scholar
- Koo HL, Neill FH, Estes MK, Munoz FM, Cameron A, DuPont HL, et al. Noroviruses: the most common pediatric viral enteric pathogen at a large university hospital after introduction of rotavirus vaccination. J Pediatric Infect Dis Soc. 2013;2:57–60. DOIPubMedGoogle Scholar
- Teunis PF, Moe CL, Liu P, Miller SE, Lindesmith L, Baric RS, et al. Norwalk virus: how infectious is it? J Med Virol. 2008;80:1468–76. DOIPubMedGoogle Scholar
- Johnston CP, Qiu H, Ticehurst JR, Dickson C, Rosenbaum P, Lawson P, et al. Outbreak management and implications of a nosocomial norovirus outbreak. Clin Infect Dis. 2007;45:534–40. DOIPubMedGoogle Scholar
- Lopman BA, Reacher MH, Vipond IB, Hill D, Perry C, Halladay T, et al. Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003. Emerg Infect Dis. 2004;10:1827–34. DOIPubMedGoogle Scholar
- Lynn S, Toop J, Hanger C, Millar N. Norovirus outbreaks in a hospital setting: the role of infection control. N Z Med J. 2004;117:U771.PubMedGoogle Scholar
- [Revised case definitions for the submission of evidence of dengue virus and norovirus and morbidity or death from dengue fever and norovirus gastroenteritis.] [in German]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011;54:246–50.PubMedGoogle Scholar
- Uhlig U, Kostev K, Schuster V, Koletzko S, Uhlig HH. Impact of rotavirus vaccination in Germany: rotavirus surveillance, hospitalization, side effects and comparison of vaccines. Pediatr Infect Dis J. 2014;33:e299–304. DOIPubMedGoogle Scholar
- Kowalzik F, Zepp F, Hoffmann I, Binder H, Lautz D, van Ewijk R, et al. Disease burden of rotavirus gastroenteritis in children residing in Germany: a retrospective, hospital-based surveillance. Pediatr Infect Dis J. 2016;35:97–103.PubMedGoogle Scholar
- Bernard H, Höhne M, Niendorf S, Altmann D, Stark K. Epidemiology of norovirus gastroenteritis in Germany 2001-2009: eight seasons of routine surveillance. Epidemiol Infect. 2014;142:63–74.PubMedGoogle Scholar
- Spackova M, Altmann D, Eckmanns T, Koch J, Krause G. High level of gastrointestinal nosocomial infections in the german surveillance system, 2002-2008. Infect Control Hosp Epidemiol. 2010;31:1273–8. DOIPubMedGoogle Scholar
- Treanor JJ, Atmar RL, Frey SE, Gormley R, Chen WH, Ferreira J, et al. A novel intramuscular bivalent norovirus virus-like particle vaccine candidate—reactogenicity, safety, and immunogenicity in a phase 1 trial in healthy adults. J Infect Dis. 2014;210:1763–71. DOIPubMedGoogle Scholar
- Bernstein DI, Atmar RL, Lyon GM, Treanor JJ, Chen WH, Jiang X, et al. Norovirus vaccine against experimental human GII.4 virus illness: a challenge study in healthy adults. J Infect Dis. 2015;211:870–8. DOIPubMedGoogle Scholar
- Beckmann MW, Juhasz-Böss I, Denschlag D, Gaß P, Dimpfl T, Harter P, et al. Surgical methods for the treatment of uterine fibroids—risk of uterine sarcoma and problems of morcellation: position paper of the DGGG. Geburtshilfe Frauenheilkd. 2015;75:148–64. DOIPubMedGoogle Scholar
- Zwink N, Jenetzky E, Schmiedeke E, Schmidt D, Märzheuser S, Grasshoff-Derr S, et al.; CURE-Net Consortium. Assisted reproductive techniques and the risk of anorectal malformations: a German case-control study. Orphanet J Rare Dis. 2012;7:65. DOIPubMedGoogle Scholar
- Statistisches Bundesamt Wiesbaden. GENESIS-Online [cited 2017 Dec 15]. https://www-genesis.destatis.de/genesis/online/logon?language=de&sequenz=statistiken&selectionname=12*&usg=ALkJrhjgxiAsKejwJNMswJxtZm3-LkALkA
- Werber D, Hille K, Frank C, Dehnert M, Altmann D, Muller-Nordhorn J, et al. Years of potential life lost for six major enteric pathogens, Germany, 2004–2008. Epidemiol Infect. 2012;•••:1–8.PubMedGoogle Scholar
- Hall AJ, Lopman BA, Payne DC, Patel MM, Gastañaduy PA, Vinjé J, et al. Norovirus disease in the United States. Emerg Infect Dis. 2013;19:1198–205. DOIPubMedGoogle Scholar
- Medizinischer Dienst der Krankenversicherung [cited 2015 Nov 22]. http://www.mdk.de
- Verhoef L, Koopmans M. W VANP, Duizer E, Haagsma J, Werber D, et al. The estimated disease burden of norovirus in the Netherlands. Epidemiol Infect. 2012;•••:1–11.PubMedGoogle Scholar
- Lopman BA, Hall AJ, Curns AT, Parashar UD. Increasing rates of gastroenteritis hospital discharges in US adults and the contribution of norovirus, 1996-2007. Clin Infect Dis. 2011;52:466–74. DOIPubMedGoogle Scholar
- Morton VK, Thomas MK, McEwen SA. Estimated hospitalizations attributed to norovirus and rotavirus infection in Canada, 2006-2010. Epidemiol Infect. 2015;143:3528–37. DOIPubMedGoogle Scholar
- Verstraeten T, Cattaert T, Harris J, Lopman B, Tam CC, Ferreira G. Estimating the burden of medically attended norovirus gastroenteritis: modeling linked primary care and hospitalization datasets. J Infect Dis. 2017;216:957–65. DOIPubMedGoogle Scholar
- Haustein T, Harris JP, Pebody R, Lopman BA. Hospital admissions due to norovirus in adult and elderly patients in England. Clin Infect Dis. 2009;49:1890–2. DOIPubMedGoogle Scholar
- Franck KT, Nielsen RT, Holzknecht BJ, Ersbøll AK, Fischer TK, Böttiger B. Norovirus genotypes in hospital settings: differences between nosocomial and community-acquired infections. J Infect Dis. 2015;212:881–8. DOIPubMedGoogle Scholar
- Geginat G, Kaiser D, Schrempf S. Evaluation of third-generation ELISA and a rapid immunochromatographic assay for the detection of norovirus infection in fecal samples from inpatients of a German tertiary care hospital. Eur J Clin Microbiol Infect Dis. 2012;31:733–7. DOIPubMedGoogle Scholar
- Rogan WJ, Gladen B. Estimating prevalence from the results of a screening test. Am J Epidemiol. 1978;107:71–6. DOIPubMedGoogle Scholar
1Current affiliation: Global Research in Infectious Diseases, Rio de Janeiro, Brazil.
Page created: October 16, 2018
Page updated: October 16, 2018
Page reviewed: October 16, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.