Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 24, Number 12—December 2018
Dispatch

Highly Pathogenic Avian Influenza A(H5N6) in Domestic Cats, South Korea

KyungHyun Lee1, Eun-Kyoung Lee1, HyunKyoung Lee, Gyeong-Beom Heo, Yu-Na Lee, Ji-Youl Jung, You-chan Bae, ByungJae So, Youn-Jeong LeeComments to Author , and Eun-Jin ChoiComments to Author 
Author affiliations: Author affiliation: Animal and Plant Quarantine Agency, Gimcheon, South Korea

Main Article

Figure 2

Maximum-likelihood phylogenetic tree of the hemagglutinin (A) and neuraminidase (B) gene segments for highly pathogenic avian influenza A(H5N6) viruses from cats, South Korea, and comparison viruses. Black circles indicate isolates from cats and triangles indicate chicken isolates from this study. Virus sequences from the GISAID EpiFlu database (http://platform.gisaid.org) and GenBank were used for each phylogenetic comparison. The genetic subclades are annotated to the right of the tree. The ge

Figure 2. Maximum-likelihood phylogenetic tree of the hemagglutinin (A) and neuraminidase (B) gene segments for highly pathogenic avian influenza A(H5N6) viruses from cats, South Korea, and comparison viruses. Black circles indicate isolates from cats and triangles indicate chicken isolates from this study. Virus sequences from the GISAID EpiFlu database (http://platform.gisaid.org) and GenBank were used for each phylogenetic comparison. The genetic subclades are annotated to the right of the tree. The genetic clusters major, minor, and G1.1.9 were designated according to the criteria of Bi et al. (2). The number at each branch indicates a bootstrap value. Scale bars indicate nucleotide substitutions per site.

Main Article

References
  1. Qi  X, Cui  L, Yu  H, Ge  Y, Tang  F. Whole-genome sequence of a reassortant H5N6 avian influenza virus isolated from a live poultry market in China, 2013. Genome Announc. 2014;2:e00706–14. DOIPubMedGoogle Scholar
  2. Bi  Y, Chen  Q, Wang  Q, Chen  J, Jin  T, Wong  G, et al. Genesis, evolution and prevalence of H5N6 avian influenza viruses in China. Cell Host Microbe. 2016;20:810–21. DOIPubMedGoogle Scholar
  3. Yu  Z, Gao  X, Wang  T, Li  Y, Li  Y, Xu  Y, et al. Fatal H5N6 avian influenza virus infection in a domestic cat and wild birds in China. Sci Rep. 2015;5:10704. DOIPubMedGoogle Scholar
  4. Li  X, Fu  Y, Yang  J, Guo  J, He  J, Guo  J, et al. Genetic and biological characterization of two novel reassortant H5N6 swine influenza viruses in mice and chickens. Infect Genet Evol. 2015;36:462–6. DOIPubMedGoogle Scholar
  5. Lee  EK, Song  BM, Lee  YN, Heo  GB, Bae  YC, Joh  SJ, et al. Multiple novel H5N6 highly pathogenic avian influenza viruses, South Korea, 2016. Infect Genet Evol. 2017;51:21–3. DOIPubMedGoogle Scholar
  6. Son  K, Kim  YK, Oem  JK, Jheong  WH, Sleeman  JM, Jeong  J. Experimental infection of highly pathogenic avian influenza viruses, Clade 2.3.4.4 H5N6 and H5N8, in Mandarin ducks from South Korea. Transbound Emerg Dis. 2018;65:899–903. DOIPubMedGoogle Scholar
  7. Lyoo  KS, Na  W, Phan  LV, Yoon  SW, Yeom  M, Song  D, et al. Experimental infection of clade 1.1.2 (H5N1), clade 2.3.2.1c (H5N1) and clade 2.3.4.4 (H5N6) highly pathogenic avian influenza viruses in dogs. Transbound Emerg Dis. 2017;64:1669–75. DOIPubMedGoogle Scholar
  8. Songserm  T, Amonsin  A, Jam-on  R, Sae-Heng  N, Meemak  N, Pariyothorn  N, et al. Avian influenza H5N1 in naturally infected domestic cat. Emerg Infect Dis. 2006;12:681–3. DOIPubMedGoogle Scholar
  9. Swayne  DE, Alexander  DJ. Confirmation of nephrotropism and nephropathogenicity of three low-pathogenic chicken-origin influenza viruses for chickens. Avian Pathol. 1994;23:345–52. DOIPubMedGoogle Scholar
  10. Bonfante  F, Fusaro  A, Zanardello  C, Patrono  LV, De Nardi  R, Maniero  S, et al. Lethal nephrotropism of an H10N1 avian influenza virus stands out as an atypical pathotype. Vet Microbiol. 2014;173:189–200. DOIPubMedGoogle Scholar
  11. Cardona  CJ, Xing  Z, Sandrock  CE, Davis  CE. Avian influenza in birds and mammals. Comp Immunol Microbiol Infect Dis. 2009;32:255–73. DOIPubMedGoogle Scholar
  12. van Riel  D, Munster  VJ, de Wit  E, Rimmelzwaan  GF, Fouchier  RA, Osterhaus  AD, et al. H5N1 virus attachment to lower respiratory tract. Science. 2006;312:399. DOIPubMedGoogle Scholar
  13. Shinya  K, Ebina  M, Yamada  S, Ono  M, Kasai  N, Kawaoka  Y. Avian flu: influenza virus receptors in the human airway. Nature. 2006;440:435–6. DOIPubMedGoogle Scholar
  14. Keawcharoen  J, Oraveerakul  K, Kuiken  T, Fouchier  RA, Amonsin  A, Payungporn  S, et al. Avian influenza H5N1 in tigers and leopards. Emerg Infect Dis. 2004;10:2189–91. DOIPubMedGoogle Scholar

Main Article

1These authors contributed equally to this article.

Page created: November 20, 2018
Page updated: November 20, 2018
Page reviewed: November 20, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external