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Volume 24, Number 4—April 2018
Dispatch

Emergomyces canadensis, a Dimorphic Fungus Causing Fatal Systemic Human Disease in North America

Ilan S. SchwartzComments to Author , Stephen Sanche, Nathan P. Wiederhold, Thomas F. Patterson, and Lynne Sigler
Author affiliations: Global Health Institute, University of Antwerp, Antwerp, Belgium (I.S. Schwartz); San Antonio Center for Medical Mycology, UT Health San Antonio, San Antonio, Texas, USA (I.S. Schwartz, N.P. Wiederhold, T.F. Patterson); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (S. Sanche); UT Health San Antonio Fungus Testing Laboratory, San Antonio (N.P. Wiederhold); South Texas Veterans Health Care System, San Antonio (T.F. Patterson); University of Alberta Biological Sciences, Edmonton, Alberta, Canada (L. Sigler)

Main Article

Table

Epidemiologic and clinical characteristics of 4 patients infected with Emergomyces canadensis, North America, 1992–2015

Case no.
Year
Location
Patient age, y/sex
Medical history
Clinical syndrome
Specimen cultured
Treatment
Outcome
Strain ID†
1
1992
Regina, Saskatchewan
68/M
HIV
Sepsis, skin lesions
Skin biopsy

Died
UAMH 7172 (AF038322)
2
2003
Saskatoon, Saskatchewan
39/M
Kidney transplant, diabetes
Pneumonia, tracheitis, lymphadenopathy, esophagitis, sepsis
Blood, BAL fluid
Fluconazole, then
amphotericin B
Survived
UAMH 10370 (EF592151)
3
2010
Colorado Springs, Colorado
75/F

Fungemia, endocervical lesion
Blood

Died
UTHSCSA DI17–85 (MG777526, MG777527)
4 2015 Santa Fe, New Mexico 40/M HIV Pneumonia, skin lesions, sepsis Skin biopsy Survived UTHSCSA DI17–84 (MG777530, MG777528)

*BAL, bronchoalveolar; ID, identification; UAMH, UAMH Centre for Global Microfungal Biodiversity; UTHSCSA, University of Texas Health Science Center at San Antonio; –, data missing.
†GenBank accession numbers for relevant nucleotide sequences are given.

Main Article

Page created: March 19, 2018
Page updated: March 19, 2018
Page reviewed: March 19, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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