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Volume 25, Number 2—February 2019
Dispatch

Crimean-Congo Hemorrhagic Fever, Kosovo, 2013–2016

Salih Ahmeti1, Lindita Berisha1, Bahrije Halili, Florim Ahmeti, Ronald von Possel, Corinna Thomé-Bolduan, Anett Michel, Simone Priesnitz, Emil C. Reisinger, Stephan Günther, Andreas Krüger, Kurtesh Sherifi, Xhevat Jakupi, Christoph J. HemmerComments to Author , and Petra Emmerich
Author affiliations: University Hasan Prishtina, Prishtina, Kosovo (S. Ahmeti); University Clinical Center of Kosovo, Prishtina (L. Berisha, B. Halili); National Institute of Public Health of Kosovo, Prishtina (F. Ahmeti, X. Jakupi); Bernhard Nocht Institute of Tropical Medicine, Hamburg, Germany (R. von Possel, C. Thomé-Bolduan, S. Günther,; P. Emmerich); Bundeswehr Hospital, Hamburg (A. Michel, S. Priesnitz, A. Krüger); University of Rostock, Rostock, Germany (E.C. Reisinger, C.J. Hemmer, P. Emmerich); University Hasan Prishtina Faculty of Agriculture and Veterinary Science, Prishtina (K. Sherifi)

Main Article

Table 1

Interdependence between clinical and laboratory findings and outcome for patients with Crimean-Congo hemorrhagic fever, Kosovo, 2013–2016*

Finding χ2 p value
Significant interdependence with outcome, with Yates correction
Clinical findings
Fasciculations 14.0 <0.001
Coma 13.2 <0.001
Somnolence 6.5 0.010
Hemoperitoneum 10.4 0.001
Bleeding gums 8.8 0.003
Hematemesis 7.7 0.005
Melena 5.7 0.017
Petechiae 5.7 0.017
Ecchymoses 5.5 0.019
Jaundice 6.2 0.013
Diarrhea 5.7 0.017
Hiccup 4.0 0.046
Laboratory findings
Viral load >1 × 108.5/mL 18.5 <0.001
LDH >2,200 U/mL 9.56 0.002
Leukocytes >7,700/µL
 7.4
 0.006
No interdependence with outcome, without Yates correction
Clinical findings
Vertigo 2.26 0.133
Hypertension 1.97 0.160
Anorexia 1.72 0.189
Nausea 1.60 0.205
Epistaxis 0.90 0.340
Vomiting 0.74 0.388
Joint pain 0.74 0.388
Sweating 0.23 0.631
Headache 0.13 0.722
Conjunctivitis 0.13 0.722
Muscular pain 0.08 0.773
Abdominal pain 0.05 0.830
Hypotension 0.03 0.864
Bradycardia <0.01 0.968
Laboratory findings
ALT >168 U/mL 1.54 0.215
AST >147 U/mL 1.47 0.225
CK >1,037 U/mL
 0.79
 0.373
Nonsignificant trend toward interdependence with outcome
Platelets <50,000/µL 3.68 0.055
With Yates correction 3.63 0.057

*ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; LDH, lactate dehydrogenase.

Main Article

1These first authors contributed equally to this article.

Page created: January 18, 2019
Page updated: January 18, 2019
Page reviewed: January 18, 2019
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