Figure 1. Overview of diagnostic testing and shedding dynamics for Zika virus and CHIKV among patients in Brazil, 2016. A) Timeline of sampling and number of samples for each test. B, C) Zika virus (B) and CHIKV (C) loads in different body fluids at 1–5 and 5–9 dpo. Black dots indicate single samples. Red dots indicate samples taken 1–5 dpo that were negative 5–9 dpo. Dotted lines indicate paired samples that were positive at both time points. Bold line indicates the median. D, E) Viral loads of Zika virus (D) and CHIKV (E) in paired urine and serum samples from individual patients, 1–5 and 5–9 dpo. Data were analyzed using GraphPad Prism 5 (GraphPad Software, Inc., https://www.graphpad.com). CHIKV, chikungunya virus; dpo, days post–symptom onset; PRNT, plaque reduction neutralization test.