Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 25, Number 4—April 2019
Dispatch

Seroprevalence of Zika and Dengue Virus Antibodies among Migrant Workers, Taiwan, 2017

Guey Chuen Perng, Tzu-Chuan Ho, Hsin-I Shih, Chia-Hua Lee, Pei-Wen Huang, Chih-Huan Chung, Nai-Ying Ko, Wen-Chien Ko, and Yu-Wen ChienComments to Author 
Author affiliations: National Cheng Kung University College of Medicine, Tainan, Taiwan (G.C. Perng, T.-C. Ho, H.-I. Shih, C.-H. Lee, P.-W. Huang, N.-Y. Ko, W.-C. Ko, Y.-W. Chien); National Cheng Kung University Hospital, Tainan (H.-I. Shih, N.-Y. Ko, W.-C. Ko, Y.-W. Chien); Kuo General Hospital, Tainan (C.-H. Chung)

Main Article

Table 2

Serostatus and neutralizing antibody titers for Zika virus and DENV among 11 migrant workers from Southeast Asia who were IgM and IgG positive for Zika virus, Taiwan, 2017*

Worker no., age, y/sex
 ELISA
Zika virus IgM
 Zika virus IgG
 DENV IgM
 DENV IgG
 90% PRNT titer
DENV-1
 DENV-2
 DENV-3
 DENV-4
 Thai
 MR766
ID01, 21/F† + + – + 10 10 <10 <10 149 399
ID02, 37/F + + – + 609 1,401 40 <10 10 <10
ID03, 28/M + + – + 138 505 11 149 438 <10
VN01, 34/M† + + – + <10 40 <10 <10 40 160
PH01, 28/F† + + – + 124 440 147 <10 1486 >2,560
PH02, 24/M† + + – + <10 10 <10 <10 227 639
PH03, 24/F† + + – + <10 <10 <10 <10 800 1279
TH01, 42/M + + – + <10 40 <10 <10 107 143
TH02, 46/M† + + – + <10 513 <10 <10 593 >2,560
TH03, 43/F + + – + 405 310 40 40 10 1,215
TH04, 31/M + + – + >2,560 1,360 1,600 10 1,468 1,599

*DENV, dengue virus; DENV-1–4, DENV serotypes 1–4; MR766, African Zika virus strain MR766; PRNT, plaque reduction neutralization test; Thai, 1 Zika virus isolate from a worker with an imported case acquired in Thailand.
†Six persons positive for Zika virus IgM fulfilled the criteria for laboratory confirmation of recent Zika virus infection adopted with definition according to the World Health Organization (7).

Main Article

References
  1. Kuan  MM, Chang  FY. Airport sentinel surveillance and entry quarantine for dengue infections following a fever screening program in Taiwan. BMC Infect Dis. 2012;12:182. DOIPubMedGoogle Scholar
  2. Fritzell  C, Rousset  D, Adde  A, Kazanji  M, Van Kerkhove  MD, Flamand  C. Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review. PLoS Negl Trop Dis. 2018;12:e0006533. DOIPubMedGoogle Scholar
  3. Ho  ZJM, Hapuarachchi  HC, Barkham  T, Chow  A, Ng  LC, Lee  JMV, et al.; Singapore Zika Study Group. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Infect Dis. 2017;17:813–21. DOIPubMedGoogle Scholar
  4. Chu  DT, Ngoc  VTN, Tao  Y. Zika virus infection in Vietnam: current epidemic, strain origin, spreading risk, and perspective. Eur J Clin Microbiol Infect Dis. 2017;36:2041–2. DOIPubMedGoogle Scholar
  5. Khongwichit  S, Wikan  N, Auewarakul  P, Smith  DR. Zika virus in Thailand. Microbes Infect. 2018;20:670–5. DOIPubMedGoogle Scholar
  6. Granger  D, Hilgart  H, Misner  L, Christensen  J, Bistodeau  S, Palm  J, et al. Serologic testing for Zika virus: comparison of three Zika virus IgM-screening enzyme-linked immunosorbent assays and initial laboratory experiences. J Clin Microbiol. 2017;55:2127–36. DOIPubMedGoogle Scholar
  7. Ward  MJ, Alger  J, Berrueta  M, Bock  H, Buekens  P, Cafferata  ML, et al. Zika virus and the World Health Organization criteria for determining recent infection using plaque reduction neutralization testing. Am J Trop Med Hyg. 2018;99:780–2. DOIPubMedGoogle Scholar
  8. Landry  ML, St George  K. Laboratory diagnosis of Zika virus infection. Arch Pathol Lab Med. 2017;141:60–7. DOIPubMedGoogle Scholar
  9. Paz-Bailey  G, Rosenberg  ES, Doyle  K, Munoz-Jordan  J, Santiago  GA, Klein  L, et al. Persistence of Zika virus in body fluids–preliminary report. N Engl J Med. 2017;379:
  10. Nicastri  E, Castilletti  C, Liuzzi  G, Iannetta  M, Capobianchi  MR, Ippolito  G. Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016. Euro Surveill. 2016;21:30314. DOIPubMedGoogle Scholar
  11. Duong  V, Lambrechts  L, Paul  RE, Ly  S, Lay  RS, Long  KC, et al. Asymptomatic humans transmit dengue virus to mosquitoes. Proc Natl Acad Sci U S A. 2015;112:14688–93. DOIPubMedGoogle Scholar
  12. Ten Bosch  QA, Clapham  HE, Lambrechts  L, Duong  V, Buchy  P, Althouse  BM, et al. Contributions from the silent majority dominate dengue virus transmission. PLoS Pathog. 2018;14:e1006965. DOIPubMedGoogle Scholar
  13. Wongsurawat  T, Athipanyasilp  N, Jenjaroenpun  P, Jun  SR, Kaewnapan  B, Wassenaar  TM, et al. Case of microcephaly after congenital infection with Asian lineage Zika virus, Thailand. Emerg Infect Dis. 2018;24:1758–61. DOIPubMedGoogle Scholar
  14. Lim  SK, Lim  JK, Yoon  IK. An update on Zika virus in Asia. Infect Chemother. 2017;49:91–100. DOIPubMedGoogle Scholar
  15. Rabaa  MA, Simmons  CP, Fox  A, Le  MQ, Nguyen  TTT, Le  HY, et al. Dengue virus in sub-tropical northern and central Viet Nam: population immunity and climate shape patterns of viral invasion and maintenance. PLoS Negl Trop Dis. 2013;7:e2581. DOIPubMedGoogle Scholar

Main Article

Page created: March 18, 2019
Page updated: March 18, 2019
Page reviewed: March 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external