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Volume 25, Number 5—May 2019

Zika Virus in Rectal Swab Samples

Camila Helena Aguiar Bôtto-Menezes, Armando Menezes Neto, Guilherme Amaral Calvet, Edna Oliveira Kara, Marcus Vinícius Guimarães Lacerda, Marcia da Costa Castilho, Ute Ströher, Carlos Alexandre Antunes de Brito, Kayvon Modjarrad, Nathalie Broutet, Patrícia Brasil, Ana Maria Bispo de Filippis, Rafael Freitas Oliveira FrancaComments to Author , and ZIKABRA Study Team
Author affiliations: Amazonas State University, Manaus, Brazil (C.H.A. Bôtto-Menezes); Tropical Medicine Foundation Doctor Heitor Vieira Dourado, Manaus (C.H.A. Bôtto-Menezes, M.V.G. Lacerda, M. da Costa Castilho); Institute Aggeu Magalhães, Recife, Brazil (A.M. Neto, C.A. Antunes de Brito, R.F.O. Franca); Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, Brazil (G.A. Calvet, P. Brasil); World Health Organization, Geneva, Switzerland (E.O. Kara, U. Ströher, N. Broutet); Oswaldo Cruz Foundation, Manaus (M.V.G. Lacerda); Walter Reed Army Institute of Research, Silver Spring, Maryland, USA (K. Modjarrad); Oswaldo Cruz Institute, Rio de Janeiro (A.M. Bispo de Filippis)

Main Article


Clinical signs and symptoms reported at enrollment visit in study of persistence of Zika virus in different body fluids of persons with confirmed infection, Brazil*

Patient ID Age, y/sex Symptoms at enrollment
191001 21/M None (asymptomatic household contact)
191002 25/M Erythema and vesicular rash, nasal congestion, sweating, upper limb muscle spasms
291001 22/F Itchy macular rash, conjunctival hyperemia, prostration, chills, taste alteration, lower back pain, arthralgia, periarticular edema, nausea, irritability
151001 38/M Itchy macular rash, headache, photophobia, retro-orbital pain, burning eyes, arthralgia (wrists, metacarpals, and phalanges), tingling hands
251001 31/F Itchy macular rash, conjunctival hyperemia, anorexia
251002 36/F Itchy macular rash, headache, conjunctival hyperemia, arthralgia (shoulders, elbows, wrists, knees, ankles), abdominal pain, periarticular edema (ankles)
251003 43/F Itchy macular rash, photophobia, retro-orbital pain, oropharyngeal pain, arthralgia (elbows and ankles)
251005 19/F Itchy macular rash, fever, headache, photophobia, conjunctival hyperemia, retro-orbital pain, muscle weakness, numbness, irritability, appetite loss, nausea
251006 65/F Itchy macular rash, fever, headache, photophobia, arthralgia (wrists, phalanges, heel, cervical spine), muscle weakness, prostration, numbness, tingling, drowsiness, abdominal pain, nausea
251007 32/F Itchy macular rash, fever, headache, retro-orbital pain, photophobia

*Reported signs and symptoms were registered after an initial rash episode following laboratory confirmation of Zika virus infection. All signs and symptoms were registered <2 d after the initial rash (except for 1 asymptomatic contact patient). Fever (>38°C) was any febrile episode reported within 30 d before the medical examination. ID, identification.

Main Article

1Team members are listed at the end of the article.

Page created: April 18, 2019
Page updated: April 18, 2019
Page reviewed: April 18, 2019
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