Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 25, Number 8—August 2019
Research Letter

Crimean-Congo Hemorrhagic Fever, Herat Province, Afghanistan, 2017

Aziz-ur-Rahman Niazi, Mohammad Jawed Jawad, Ahmad Amirnajad, Peter A. Durr, and David T. WilliamsComments to Author 
Author affiliations: Herat University, Herat, Afghanistan (A.-u.-R. Niazi, M.J. Jawad); Department of Public Health, Herat (A. Amirnajad); CSIRO,; Australian Animal Health Laboratory, Geelong, Victoria, Australia (P.A. Durr, D.T. Williams)

Main Article


Laboratory findings and clinical and hemorrhagic features for patients hospitalized with Crimean-Congo hemorrhagic fever, Herat Province, Afghanistan, 2017*

Type of hemorrhage
Ecchymosis 42 (66.7)
Epistaxis 36 (57.1)
Hemoptysis 12 (19.1)
Hematemesis 10 (15.9)
Melana 7 (11.1)
Petechia 4 (6.4)
Gum bleeding 3 (4.8)

*ALT, alanine aminotransferase; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; PT, prothrombin time.
†<50 × 109/L (reference 150–450 × 109/L) (6).
‡>200 U/L (reference 5–40 U/L) (7).
§>150 U/L (reference 7–56 U/L) (7).

Main Article

  1. Shayan  S, Bokaean  M, Shahrivar  MR, Chinikar  S. Crimean-Congo hemorrhagic fever. Lab Med. 2015;46:1809. DOIPubMedGoogle Scholar
  2. Mertens  M, Schmidt  K, Ozkul  A, Groschup  MH. The impact of Crimean-Congo hemorrhagic fever virus on public health. Antiviral Res. 2013;98:24860. DOIPubMedGoogle Scholar
  3. Mustafa  ML, Ayazi  E, Mohareb  E, Yingst  S, Zayed  A, Rossi  CA, et al. Crimean-Congo hemorrhagic fever, Afghanistan, 2009. Emerg Infect Dis. 2011;17:19401. DOIPubMedGoogle Scholar
  4. Niazi A-u-R. Clinical epidemiology of Crimean-Congo hemorrhagic fever in west region of Afghanistan. Herat (Afghanistan): Herat University Press; 2017.
  5. World Health Organization. Communicable disease profile. Afghanistan and neighboring countries. January 2002 [cited 2012 Apr 17].
  6. Hui  P, Cook  DJ, Lim  W, Fraser  GA, Arnold  DM. The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review. Chest. 2011;139:2718. DOIPubMedGoogle Scholar
  7. Swanepoel  R, Gill  DE, Shepherd  AJ, Leman  PA, Mynhardt  JH, Harvey  S. The clinical pathology of Crimean-Congo hemorrhagic fever. Rev Infect Dis. 1989;11(Suppl 4):S794800. DOIPubMedGoogle Scholar
  8. Tezer  H, Polat  M. Diagnosis of Crimean-Congo hemorrhagic fever. Expert Rev Anti Infect Ther. 2015;13:55566. DOIPubMedGoogle Scholar
  9. Bastug  A, Kayaaslan  B, Kazancioglu  S, Aslaner  H, But  A, Akinci  E, et al. Crimean-Congo hemorrhagic fever: prognostic factors and the association of leukocyte counts with mortality. Jpn J Infect Dis. 2016;69:515. DOIPubMedGoogle Scholar
  10. Chamberlain  J, Atkinson  B, Logue  CH, Latham  J, Newman  ENC, Hewson  R. Genome sequence of ex-Afghanistan Crimean-Congo hemorrhagic fever virus SCT strain, from an imported United Kingdom case in October 2012. Genome Announc. 2013;1:e0016113. DOIPubMedGoogle Scholar

Main Article

Page created: July 16, 2019
Page updated: July 16, 2019
Page reviewed: July 16, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.