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Volume 25, Number 9—September 2019
Research Letter

Worldwide Reduction in MERS Cases and Deaths since 2016

Christl A. Donnelly, Mamun R. Malik, Amgad Elkholy, Simon Cauchemez, and Maria D. Van KerkhoveComments to Author 
Author affiliations: University of Oxford, Oxford, UK (C.A. Donnelly); Imperial College London, London, UK (C.A. Donnelly); World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt (M.R. Malik, A. Elkholy); Institut Pasteur, Paris, France (S. Cauchemez); World Health Organization, Geneva, Switzerland (M.D. Van Kerkhove)

Main Article

Table

Estimated Middle East respiratory syndrome cases and deaths averted because of reduced human-to-human transmission and camel-to-human transmission*

Year Estimated cases and deaths averted because of reduced human-to-human transmission†
Estimated cases and deaths averted because of reduced
camel-to-human and human-to-human transmission
Cases averted‡ 2-sided p value Deaths averted
Cases averted‡ 2-sided p value Deaths averted
Assuming 20% CFR‡ Assuming 35.5% CFR‡ Assuming 20% CFR‡ Assuming 35.5% CFR‡
2016 154 (0–495) 0.2714 31 (0–99) 55 (0–176) 507 (189–967) <0.0001 101 (38–193) 180 (67–343)
2017 96 (0–419) 0.5810 19 (0–84) 34 (0–149) 507 (189–967) <0.0001 101 (38–193) 180 (67–343)
2018§
80 (0–338)
0.4316
16 (0–68)
29 (0–120)

451 (191–855)
<0.0001
90 (38–171)
160 (68–304)
2016–2018§ 330 (0–819) 0.0896 66 (0–164) 117 (0–291) 1,465 (895–2165) <0.0001 293 (179–433) 520 (318–769)

*Values are estimated no. (95% range) except as indicated. CFR, case-fatality ratio.
†Conditional on reported community-acquired cases.
‡The 95% intervals reported are the 2.5th and 97.5th percentiles of the simulations. When cases averted were not statistically significant, we truncated the lower bound of the 95% CI to 0 cases averted.
§Through September 2018.

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Page created: August 21, 2019
Page updated: August 21, 2019
Page reviewed: August 21, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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