Association of Enterovirus D68 with Acute Flaccid Myelitis, Philadelphia, Pennsylvania, USA, 2009–2018
Priyanka Uprety, Darcy Curtis, Michael Elkan, Jeffrey Fink, Ramakrishnan Rajagopalan, Chunyu Zhao, Kyle Bittinger, Stephanie Mitchell, Erlinda R. Ulloa, Sarah Hopkins, and Erin H. Graf
Author affiliations: Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA (P. Uprety, D. Curtis, M. Elkan, J. Fink, R. Rajagopalan, C. Zhao, K. Bittinger, E.R. Ulloa, S. Hopkins, E.H. Graf); University of Pennsylvania, Philadelphia (P. Uprety, K. Bittinger, S. Mitchell, E.R. Ulloa, S. Hopkins, E.H. Graf)
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Figure 2
Figure 2. Phylogenetic relationships between Philadelphia whole enterovirus D68 (EV-D68) genomes, including AFM cases, Philadelphia, Pennsylvania, USA, 2009–2018. EV-D68 polyprotein sequences from GenBank (n = 55) and this study (n = 28) were used to build a maximum-likelihood tree. EV-D68 clades, defined in prior publications, are indicated. Sequences from this study are indicated in bold, and AFM cases are indicated with that prefix. AFM, acute flaccid myelitis. Scale bar indicates nucleotide substitutions per site.
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