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Volume 26, Number 1—January 2020
Research Letter

Autochthonous Human Fascioliasis, Belgium

Sandrine Milas1Comments to Author , Camelia Rossi, Ivan Philippart, Pierre Dorny, and Emmanuel Bottieau
Author affiliations: University Hospital Center Tivoli, La Louvière, Belgium (S. Milas); University Hospital Center Ambroise Paré, Mons, Belgium (C. Rossi); Regional Hospital Mons-Hainaut, Mons (I. Philippart); Institute of Tropical Medicine, Antwerp, Belgium (P. Dorny, E. Bottieau)

Main Article


Clinical, laboratory, and radiologic features of 2 autochthonous cases of human fascioliasis, Mons, Belgium, 2008–2009*

Features Case 1 Case 2
Patient age, y/sex 72/M 59/F
Date of initial examination
Nov 2008
Dec 2008
Laboratory tests, date
Eosinophil cell count/mL (% leukocytes)†
Nov 2008 9,688 (56) ND
Dec 2008 7,504 (56) 6,750 (43)
Mar 2009 8,830 (56.6) 8,525 (55)
1 mo after triclabendazole 627 (10.8) 3,526 (41)
5 mo after triclabendazole 512 (8.4) 812 (14.5)
Aspartate aminotransferases, IU/L‡
Nov 2008 53 ND
Dec 2008 30 21
Mar 2009 25 23
1 mo after triclabendazole 26 32
5 mo after triclabendazole
Serologic test (method), date Dec 2008 Jan 2009
Ascaris spp. (immunodiffusion)
Echinococcus granulosus (ELISA)
Echinococcus multilocularis (ELISA) ND
Toxocara spp. (ELISA)
Taenia solium ND
Trichinella spiralis (ELISA) +
Fasciola (indirect hemagglutination), Mar 2009§ 1/640 1/2,560
1 mo. after triclabendazole 1/640 ND
5 mo. after triclabendazole 1/320 1/320
Abdominal CT, date Nov 2008, multiple hypodense liver nodules Mar 2009, multiple hypodense liver nodules
Liver biopsy, date
Dec 2008, chronic active hepatitis with acute necrosis, presence of eosinophils in portal spaces
*Both case-patients had an early acute phase of disease during Sep–Dec 2008 with high fever, abdominal pain, generalized itching, and urticarial skin rash. Both cases then had a later disease phase during Nov 2008–Mar 2009 with persistent fatigue and weight loss. CT, computed tomography; IU, International Units; ND, not done; –, negative; +, positive.
†Normal values, 0–400/mL (<7%).
‡Normal values 10–40 IU/L.
§Normal value <1/320.

Main Article

1Current affiliation: University Center of Charleroi, Charleroi, Belgium.

Page created: December 18, 2019
Page updated: December 18, 2019
Page reviewed: December 18, 2019
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