Recombinant Nontypeable Genotype II Human Noroviruses in the Americas
Kentaro Tohma
, Cara J. Lepore, Juan I. Degiuseppe, Juan A. Stupka, Mayuko Saito, Holger Mayta, Mirko Zimic, Lauren A. Ford-Siltz, Robert H. Gilman, and Gabriel I. Parra
Author affiliations: US Food and Drug Administration, Silver Spring, Maryland, USA (K. Tohma, C.J. Lepore, L.A. Ford-Siltz, G.I. Parra); INEI-ANLIS “Dr. Carlos G. Malbrán,” Buenos Aires, Argentina (J.I. Degiuseppe, J.A. Stupka); Tohoku University Graduate School of Medicine, Sendai, Japan (M. Saito); Universidad Peruana Cayetano Heredia, Lima, Peru (H. Mayta, M. Zimic); Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA (R.H. Gilman)
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Figure
Figure. Phylogenetic analyses of nontypeable norovirus GII strains locally distributed in the Americas. Maximum-likelihood phylogenetic trees of the RNA-dependent RNA polymerase–-encoding nucleotide sequences (>771 nt) (A), major capsid protein–encoding nucleotide sequences (>1,605 nt) (B), and the minor capsid protein–encoding nucleotide sequences (>536 nt) (C) from human GII norovirus strains were created by using the Tamura-Nei model. Yellow highlighting indicates strains detected in this study; red branches and arrows indicate the divergence of a group of nontypeable GII strains reported in the Americas; and black arrow indicates GII.3 strains that diverged in the same branches with nontypeable GII strains. Bootstrap values (>70) from 100 replicates are shown on the nodes. GenBank accession numbers are shown. Scale bars indicate genetic distance (nucleotide substitutions/site).
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