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Volume 26, Number 10—October 2020
Dispatch

Seawater-Associated Highly Pathogenic Francisella hispaniensis Infections Causing Multiple Organ Failure

Hua Zhou1, Qing Yang1, Lisha Shen, Yake Yao, Jun Xu, Junhui Ye, Xiaomai Wu, Yunsong Yu, Ziqin Li, Jianying ZhouComments to Author , and Shangxin YangComments to Author 
Author affiliations: The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (H. Zhou, L. Shen, Y. Yao, J. Xu, J. Zhou); State Key Laboratory for Diagnostic and Treatment of Infectious Diseases, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou (Q. Yang); Sanmen People’s Hosptial, Taizhou, China (J. Ye); Taizhou Hospital, Taizhou (X. Wu); Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou (Y. Yu); Zhejiang-California International Nanosystems Institute, Zhejiang University, Hangzhou (Z. Li, S. Yang); UCLA School of Medicine, Los Angeles, California, USA (S. Yang)

Main Article

Table 2

Drug susceptibility testing results of a Francisella hispaniensis isolate from a 64-year-old fisherman, China

Antimicrobial drug Interpretation* MIC, μg/mL
Amikacin S <2
Colistin R >16
Levofloxacin S ≤0.12
Trimethoprim/sulfamethoxazole R >320
Tobramycin S <1
Piperacillin/tazobactam S <4
Cefoperazone/sulbactam R >64
Ciprofloxacin S <0.25
Imipenem R >16
Minocycline S <1
Ceftazidime R >64
Cefepime S 4
Meropenem R >16
Tigecycline S <0.5
Kanamycin NA 2
Chloramphenicol NA 2
Erythromycin NA 1
Azithromycin NA 0.5
Amoxicillin/clavulanic acid NA >32

*Interpretation was based on the breakpoints for Non-Enterobacteriaceae (5). NA, breakpoint not available; R, resistant; S, susceptible.

Main Article

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1These authors contributed equally to this article.

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