Multidrug-Resistant Hypervirulent Group B Streptococcus in Neonatal Invasive Infections, France, 2007–2019
Céline Plainvert, Constantin Hays
1, Gérald Touak, Caroline Joubrel-Guyot
2, Nicolas Dmytruk, Amandine Frigo, Claire Poyart, and Asmaa Tazi
Author affiliations: Assistance Publique–Hôpitaux de Paris Centre Université de Paris, Paris, France (C. Plainvert, C. Hays, C. Joubrel-Guyot, N. Dmytruk, A. Frigo, C. Poyart, A. Tazi); Institut Cochin, Paris (C. Plainvert, G. Touak, C. Poyart, A. Tazi); FHU Prema, Paris (C. Plainvert, C. Poyart, A. Tazi); Université de Paris, Paris (C. Hays, C. Joubrel-Guyot, C. Poyart, A. Tazi)
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Figure 2
Figure 2. Increasing prevalence of MDR CC17 GBS among neonatal invasive isolates, France, 2007–2019. The annual proportion of infections caused by MDR CC17 GBS, such as those harboring the determinants tet(O), erm(B), and aphA-3, during EOD (blue line), LOD (red line) and overall (black line) are represented. Results are expressed as percentage of total GBS isolates per syndrome and per year. Error bars indicate 95% CIs. Evolutionary trends were analyzed using 2-tailed nonparametric Spearman correlation. CC, clonal complex; EOD, early-onset disease; GBS, group B Streptococcus; LOD, late-onset disease; MDR, multidrug-resistant.
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