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Volume 26, Number 11—November 2020
Dispatch

Multidrug-Resistant Candida auris Infections in Critically Ill Coronavirus Disease Patients, India, April–July 2020

Anuradha ChowdharyComments to Author , Bansidhar Tarai, Ashutosh Singh, and Amit Sharma
Author affiliations: Vallabhbhai Patel Chest Institute of the University of Delhi, New Delhi, India (A. Chowdhary, A. Singh); Max Health Care Institute, New Delhi (B. Tarai); International Centre for Genetic Engineering and Biotechnology, New Delhi (A. Sharma)

Main Article

Table 2

Drug MICs for Candida spp.in 15 coronavirus disease patients, India, April–July 2020*

Drug Patient no. (Candida sp.), drug MIC, μg/mL
1 (C. auris) 2 (C. auris) 3 (C. auris) † 4 (C. auris) 5 (C. auris) 6 (C. auris) † 7 (C. auris) 8 (C. auris) 9 (C. auris) 10 (C. auris) 11 (C. tropicalis) 12 (C. albicans) 13 (C. albicans) 14 (C. albicans) 15 (C. krusei)
FLU 512 256 256/256 512 256 256/256 512 256 256 512 0.25 0.5 0.5 0.5 16
VRC 2 0.5 1/1 1 1 1/0.5 0.25 2 2 0.125 0.03 0.125 0.125 0.125 0.125
ISA 0.5 0.25 0.125/0.25 0.03 0.06 0.125/0.25 0.5 0.06 0.06 0.06 0.015 0.125 0.125 0.125 0.125
POS 0.25 0.125 0.125/0.125 0.015 0.06 0.03/0.03 0.125 0.06 0.03 0.06 0.015 0.125 0.25 0.25 0.25
AMB 0.5 0.5 0.125/0.25 0.5 2 1/1 2 4 1 4 0.5 0.5 0.5 0.5 0.5
CAS 2 2 2/4 1 0.5 0.5/0.25 0.25 1 0.5 1 1 0.125 0.125 0.125 10.5
AFG 0.125 0.25 0.25/0.5 0.125 0.25 0.125/0.25 0.5 0.125 0.125 0.25 0.06 0.06 0.03 0.03 0.125
MFG 0.06 0.25 0.5/0.5 0.06 0.03 0.25/0.125 0.125 0.25 0.125 0.125 0.06 0.06 0.06 0.06 0.125
5-FC 32 8 8/16 1 1 64/64 64 64 64 64 0.125 0.5 1 1 16

*AFG, anidulafungin; AMB, amphotericin B; CAS, caspofungin; FLC, fluconazole; ISA, isavuconazole; MFG, micafungin; POS, posaconazole; VRC, voriconazole; 5-FC, 5-flucytosine.
†C. auris isolated from blood and urine.

Main Article

Page created: August 18, 2020
Page updated: October 19, 2020 1:41 PM EDT
Page reviewed: October 19, 2020 1:41 PM EDT
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