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Volume 26, Number 12—December 2020
Research

Human-Pathogenic Kasokero Virus in Field-Collected Ticks

Amy J. Schuh, Brian R. Amman, Ketan Patel, Tara K. Sealy, Robert Swanepoel, and Jonathan S. TownerComments to Author 
Author affiliations: US Public Health Service Commissioned Corps, Rockville, Maryland, USA (A.J. Schuh); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.J. Schuh, B.R. Amman, K. Patel, T.K. Sealy, J.S. Towner); University of Pretoria, Onderstepoort, South Africa (R. Swanepoel)

Main Article

Figure 2

Maximum-likelihood phylogenies constructed from virus sequences belonging to the species Kasokero orthonairovirus, including viruses collected from Ornithodoros (Reticulinasus) faini tick pools from Rousettus aegyptiacus bats, western Uganda, 2013 and 2017. The midpoint rooted phylogenies were generated from complete nucleoprotein (N) (A), glycoprotein precursor (GP) (B), and RNA-dependent RNA-polymerase (RdRp) (C) gene sequences. The N and RdRp gene phylogenies were generated using the general time-reversible nucleotide substitution model with the addition of invariant sites, and the GP gene phylogeny was generated using the general time-reversible nucleotide substitution model with a gamma distribution of rates across sites. Horizontal branch lengths are proportional to the genetic distance between the sequences. Numbers at the end of the branches represent percent bootstrap values based on 1,000 replicates. Only percent bootstrap values >50% are shown. GenBank accession numbers for the new Kasokero virus tick sequences from this study are MT309080–98. Scale bars indicate nucleotide substitutions per site.

Figure 2. Maximum-likelihood phylogenies constructed from virus sequences belonging to the species Kasokero orthonairovirus, including viruses collected from Ornithodoros (Reticulinasus) faini tick pools from Rousettus aegyptiacus bats, western Uganda, 2013 and 2017. The midpoint rooted phylogenies were generated from complete nucleoprotein (N) (A), glycoprotein precursor (GP) (B), and RNA-dependent RNA-polymerase (RdRp) (C) gene sequences. The N and RdRp gene phylogenies were generated using the general time-reversible nucleotide substitution model with the addition of invariant sites, and the GP gene phylogeny was generated using the general time-reversible nucleotide substitution model with a gamma distribution of rates across sites. Horizontal branch lengths are proportional to the genetic distance between the sequences. Numbers at the end of the branches represent percent bootstrap values based on 1,000 replicates. Only percent bootstrap values >50% are shown. GenBank accession numbers for the new Kasokero virus tick sequences from this study are MT309080–98. Scale bars indicate nucleotide substitutions per site.

Main Article

Page created: October 16, 2020
Page updated: November 19, 2020
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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