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Volume 26, Number 2—February 2020
Research

Cost-effectiveness of Screening Program for Chronic Q Fever, the Netherlands

Pieter T. de BoerComments to Author , Marit M.A. de Lange, Cornelia C.H. Wielders, Frederika Dijkstra, Sonja E. van Roeden, Chantal P. Bleeker-Rovers, Jan Jelrik Oosterheert, Peter M. Schneeberger, and Wim van der Hoek
Author affiliations: National Institute for Public Health and the Environment, Bilthoven, the Netherlands (P.T. de Boer, M.M.A. de Lange, C.C.H. Wielders, F. Dijkstra, W. van der Hoek); University Medical Centre Utrecht, Utrecht, the Netherlands (S.E. van Roeden, J.J. Oosterheert); Radboud university medical center, Nijmegen, the Netherlands (C.P. Bleeker-Rovers); Jeroen Bosch Hospital, ’s-Hertogenbosch, the Netherlands (P.M. Schneeberger)

Main Article

Table 1

Subgroup criteria in a study of the cost-effectiveness of screening for CQF, the Netherlands, 2017*

Category
 Condition
Area of residence
High incidence >50 acute QF notifications/100,000 inhabitants and >2 acute QF notifications OR presence of a farm with QF abortion waves† within a 5-km range during the epidemic period.
Middle incidence 10–49 acute QF notifications/100,000 inhabitants and >2 acute QF notifications OR presence of a farm that tested positive in the mandatory bulk tank milk monitoring initiated during the QF epidemic.
Low incidence
 <10 acute QF notifications/100,000 inhabitants OR <2 notifications during the epidemic period.
Preexisting risk factor
Diagnosed cardiovascular risk factor Heart valve disorder (all types of defects), heart valve prosthesis, aortic aneurysm, prosthesis/stent, history of endocarditis and congenital heart anomalies.
Immunocompromised patients HIV infection, asplenia, spleen disorder, malignancy or bone marrow transplantation, and patients using immunosuppressant drugs. As proxy for patients using immunosuppressant drugs, prevalence data were used of rheumatoid arthritis patients and patients with inflammatory bowel disease, assuming these patients frequently use immunosuppressant medication.
Unknown, >60 y Age >60 y AND no or undiagnosed cardiovascular risk factor, e.g., heart valve disorder, aortic aneurysm.
Unknown 18–59 y Age 18–59 y AND no or undiagnosed cardiovascular risk factor, e.g., heart valve disorder, aortic aneurysm.

*The epidemic period was 2007–2010. QF, Q fever.
†Abortion of >5% of pregnant goats in a farm over a 4-week period.

Main Article

Page created: January 17, 2020
Page updated: January 17, 2020
Page reviewed: January 17, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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