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Volume 26, Number 2—February 2020

Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses

Helen E. EverettComments to Author , Bethany Nash, Brandon Z. Londt1, Michael D. Kelly, Vivien Coward, Alejandro Nunez, Pauline M. van Diemen, Ian H. Brown, and Sharon M. Brookes
Author affiliations: Animal and Plant Health Agency, Weybridge, UK

Main Article


Influenza virus strains of swine or human origin used for analysis of swine influenza A virus containing genes from pH1N1 and swine influenza A(H1N2) viruses*

Virus strain
Gene segment origin†
Internal cassette
A/swine/England/1382/2010 H1N2r H1huN2‡ pH1N1 In vivo, in vitro (8)
A/swine/England/1353/2009 Sw/pdm09 pH1N1 pH1N1 In vitro (28)
A/swine/England/997/2008 H1huN2‡ H1huN2‡ H1avN1 In vitro (6)
A/England/195/2009 Hu/pdm09 pH1N1 pH1N1 HI (29)
A/swine/England/201635/1992 H3N2 H3N2‡ H1avN1 HI (30)
A/swine/England/195852/1992 H1avN1 H1avN1 H1avN1 HI (31)
A/swine/England/104270/2011 H1huN2‡ H1huN2‡ H1avN1 HI (Animal and Plant Health Agency, unpub. data)

*Av, avian; HA, hemagglutinin; HI, hemagglutination inhibition; hu, human; NA, neuraminidase; pH1N1, influenza A(H1N1)pdm09; Sw, swine.
†Gene segment origin refers to the virus lineage origin of gene segments encoding the HA and NA envelope proteins or the remaining gene segments of the internal gene cassette.
‡Swine virus gene segments previously derived from human-origin viruses.

Main Article

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1Current affiliation: hVIVO Services Limited, London, UK.

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