Volume 26, Number 2—February 2020
Research
Neutralizing Antibodies against Enteroviruses in Patients with Hand, Foot and Mouth Disease
Table 2
Virus | Immunity status | Virus, no. (%) samples |
|||
---|---|---|---|---|---|
CVA6 | CVA10 | CVA16 | EV-A71 | ||
CVA6 | Seropositivity | ||||
At enrollment | 2 (7) | 10 (33) | 5 (17) | 2 (7) | |
At follow-up | 30 (100) | 9 (30) | 9 (30) | 3 (10) | |
p value | <0.001 | 1.0 | 0.36 | 1.0 | |
Seroconversion |
28 (93) |
1 (3) |
7 (23) |
2 (7) |
|
CVA10 | Seropositivity | ||||
At enrollment | 4 (13) | 9 (30) | 3 (10) | 3 (10) | |
At follow-up | 6 (20) | 29 (97) | 4 (13) | 5 (17) | |
p value | 0.73 | <0.001 | 1.0 | 0.71 | |
Seroconversion |
4 (13) |
25 (83) |
3 (10) |
2 (7) |
|
CVA16 | Seropositivity | ||||
At enrollment | 7 (23) | 10 (33) | 8 (27) | 5 (17) | |
At follow-up | 9 (30) | 11 (37) | 30 (100) | 7 (23) | |
p value | 0.77 | 1.0 | <0.001 | 0.75 | |
Seroconversion |
3 (10) |
2 (7) |
23 (77) |
2 (7) |
|
EV-A71 | Seropositivity | ||||
At enrollment | 5 (17) | 17 (57) | 6 (20) | 18 (60) | |
At follow-up | 7 (23) | 14 (47) | 8 (27) | 30 (100) | |
p value | 0.75 | 0.61 | 0.76 | <0.001 | |
Seroconversion | 4 (13) | 1 (3) | 3 (10) | 17 (57) |
*n = 30 for each virus. p values reflect the results of statistical analysis comparing the seropositive rates between the 2 time points (enrollment and follow-up) of the corresponding enterovirus serotypes. CV, coxsackievirus; EV, enterovirus.
Page created: January 17, 2020
Page updated: January 17, 2020
Page reviewed: January 17, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.