Volume 26, Number 3—March 2020
Research
Pregnancy Outcomes among Women Receiving rVSVΔ-ZEBOV-GP Ebola Vaccine during the Sierra Leone Trial to Introduce a Vaccine against Ebola
Table 2
Pregnancy outcome by risk for vaccine viremia during pregnancy among 48 women with estimated date of conception <60 days from vaccination, Sierra Leone Trial to Introduce a Vaccine against Ebola*
Characteristic | Live birth | Pregnancy loss | Total | Barnard’s exact p value |
---|---|---|---|---|
Immediate vaccinated, no. | 17 | 14 | 31 | 1 |
High viremia risk | 5 (56) | 4 (44) | 9 | NA |
Low viremia risk |
12 (55) |
10 (45) |
22 |
NA |
Deferred crossover vaccinated, no. | 12 | 5 | 17 | 0.75 |
High viremia risk | 6 (75) | 2 (25) | 8 | NA |
Low viremia risk |
6 (67) |
3 (33) |
9 |
NA |
Total vaccinated, no. | 29 | 19 | 48 | 0.69 |
High viremia risk | 11 (65) | 6 (35) | 17 | NA |
Low viremia risk | 18 (58) | 13 (42) | 31 | NA |
*Values are no. (%) except as indicated. NA, not applicable.
†High viremia risk is defined as estimated date of conception before vaccination or 0–14 days after vaccination. Low viremia risk is defined as estimated date of conception 15–60 days after vaccination.
1These first authors contributed equally to this article.
2These authors were co–principal investigators.