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Volume 26, Number 4—April 2020
Research

Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India

Shilpa NaikComments to Author , Matthew L. Robinson, Mallika Alexander, Ajay Chandanwale, Pradip Sambarey, Aarti Kinikar, Renu Bharadwaj, Gajanan N. Sapkal, Puja Chebrolu, Prasad Deshpande, Vandana Kulkarni, Smita Nimkar, Vidya Mave, Amita Gupta, and Jyoti Mathad
Author affiliations: Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India (S. Naik, A. Chandanwale, P. Sambarey, A. Kinikar, R. Bharadwaj); Johns Hopkins School of Medicine, Baltimore, Maryland, USA (M.L. Robinson, A. Gupta); Byramjee Jeejeebhoy Government Medical College–Johns Hopkins Clinical Trials Unit, Pune (M. Alexander, P. Deshpande, V. Kulkarni, S. Nimkar, V. Maye); National Institute of Virology, Pune (G.N. Sapkal); Weill Cornell Medical College, New York, New York, USA (P. Chebrolu, J. Mathad)

Main Article

Table 3

Birth outcomes by maternal dengue infection status among 42 deliveries analyzed by intensified short symptom screening program for dengue infection during pregnancy, India*

Clinical characteristic All births, n = 42 Maternal dengue positive, n = 6 Maternal dengue negative, n = 34 OR (95% CI) p value
Gestational age, wk 38 (37–39) 37.7 (37.2–38.1) 39.1 (37.9–39.9) 1.0 (0.7–1.5) 0.28
Cesarean section 10 (24) 1 (17) 9 (26) 0.6 (0–6.1) 1
Premature 9 (21) 1 (17) 8 (24) 0.7 (0–7.3) 1
Low birthweight 10 (24) 2 (33) 7 (21) 1.9 (0.1–16.8) 0.60
Head circumference <3rd percentile† 9 (21) 2 (33) 7 (22)‡ 1.8 (0.1–15.6) 0.60
Head circumference <10th percentile† 14 (33) 2 (33) 12 (38)‡ 0.8 (0.1–6.9) 1
Stillbirth 1 (2) 0 (0) 1 (3) 0 (0–220.2) 1
Deceased at birth or before 6-mo follow-up§ 3 (7) 0 (0) 3 (9) 0 (0–15) 1
Oligohydramnios 2 (5) 1 (17) 1 (3) 6.1 (0.1–530.4) 0.28
Apgar score at 1 min 8 (7–8) 8 (8–8) 8 (7–8) 2.1 (0.4–16.2) 0.36
Apgar score at 5 min 9 (9–9) 9 (9–9) 9 (9–9) 0.9 (0.3–6.7) 0.65

*Values are no. (%) or no. (range). OR, odds ratio.
†Intergrowth standards.
‡Head circumference data were not available for 2 infants.
§Six-month follow-up data were available for 22 infants.

Main Article

Page created: March 17, 2020
Page updated: March 17, 2020
Page reviewed: March 17, 2020
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