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Volume 26, Number 5—May 2020
Synopsis

Epidemiology of Tick-Borne Relapsing Fever in Endemic Area, Spain

María Carmen DomínguezComments to Author , Salvador Vergara, María Carmen Gómez, and María Esther Roldán
Author affiliations: Hospital de la Merced, Osuna, Spain (M.C. Domínguez, M.C. Gómez, M.E. Roldán); Hospital del Tomillar, Seville, Spain (S. Vergara)

Main Article

Table 4

Factors associated with risk for JHR among 79 cases of tick-borne relapsing fever, Spain*

Variable Value
 p value† Adjusted OR (95% CI) p value‡
Sex 0.13 NS
F 1 (1.3)
M
 7 (8.9)
Median age, y (IQR) 0.86 NS
Y 28.6 (17.3–46.3)
N
 25.5 (18.9–48.7)
Rural environment 0.57 NS
Y 7 (8.9)
N
 1 (1.3)
Contact with rodents 0.11 NS
Y 3 (3.8)
N
 5 (6.3)
Hepatomegaly 0.46 NS
Y 0
N
 8 (10.1)
Splenomegaly 0.49 NS
Y 1 (1.3)
N
 7 (8.9)
Jaundice 0.9 NS
Y 0
N
 8 (10.1)
Petechiae 0.9 NS
Y 0
N
 8 (10.1)
Meningeal signs 0.9 NS
Y 0
N
 8 (10.1)
Exanthema 0.28 NS
Y 1 (1.3)
N
 7 (8.9)
Tick bite 0.17 NS
Y 3 (3.8)
N
 5 (6.3)
Tetracycline 0.54 NS
Y 7 (8.9)
N
 1 (1.3)
Cephalosporin 0.31 NS
Y 2 (2.5)
N
 6 (7.6)
Macrolides 0.35 NS
Y 1 (1.3)
N
 7 (8.9)
Median length of clinical signs, d (IQR)§ 0.36 NS
Y 3 (2–5.8)
N
 3 (1.3–4)
Median length of hospital admission, d (IQR) 0.004 0.56 (0.29–1.02) 0.057
Y 5 (4–7)
N
 3 (3–3.3)
Median duration of antimicrobial therapy, d (IQR) 0.55 NS
Y 10 (8–14)
N
 10 (9–11.8)
*Values are no. (%) patients with JHR except as indicated. IQR, interquartile range; JHR, Jarisch-Herxheimer reaction; NS, not statistically significant; OR, odds ratio.
†Univariant analysis calculated by using χ2 or Fisher exact test.
‡Multivariant analysis calculated by using Student t-test or Mann-Whitney U-test.
§Values represent findings from 36 patients with known length of clinical signs.

Main Article

Page created: April 16, 2020
Page updated: April 16, 2020
Page reviewed: April 16, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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