Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 26, Number 5—May 2020
Research Letter

Fatal Rodentborne Leptospirosis in Prison Inmates, South Africa, 2015

Kovashnee NaidooComments to Author , Mark Moseley, Kerrigan McCarthy, Ruvimbo Chingonzoh, Charlene Lawrence, Grace M. Setshedi, John Frean, and Jennifer Rossouw
Author affiliations: National Institute for Communicable Diseases, a division of the National Health Laboratory Service, Johannesburg, South Africa (K. Naidoo, K. McCarthy, R. Chingonzoh, G.M. Setshedi, J. Frean, J. Rossouw); University of Aberdeen, Aberdeen, Scotland, UK (M. Moseley); Western Cape Government: Health, Cape Town, South Africa (C. Lawrence); University of the Witwatersrand, Johannesburg (J. Frean)

Main Article

Figure

Neighbor-joining phylogenetic tree based of 256 bp of Leptospira lfb1 gene of isolates from South Africa and reference sequences. Leptospira sequences collected during this study are labeled according to sample source (rodent, water) and the number of sequences indicated. Reference sequences include lfb1 sequences from isolates obtained from human cases of leptospirosis in New Caledonia (3). GenBank accession numbers are provided in parentheses. Scale bar indicates nucleotide substitutions per s

Figure. Neighbor-joining phylogenetic tree based on 256 bp of Leptospira lfb1 gene of isolates from South Africa and reference sequences. Leptospira sequences collected during this study are labeled according to sample source (rodent, water) and the number of sequences indicated. Reference sequences include lfb1 sequences from isolates obtained from human cases of leptospirosis in New Caledonia (3). GenBank accession numbers are provided in parentheses. Scale bar indicates nucleotide substitutions per site.

Main Article

References
  1. Costa  F, Hagan  JE, Calcagno  J, Kane  M, Torgerson  P, Martinez-Silveira  MS, et al. Global morbidity and mortality of leptospirosis: a systematic review. PLoS Negl Trop Dis. 2015;9:e0003898. DOIPubMedGoogle Scholar
  2. Merien  F, Portnoi  D, Bourhy  P, Charavay  F, Berlioz-Arthaud  A, Baranton  G. A rapid and quantitative method for the detection of Leptospira species in human leptospirosis. FEMS Microbiol Lett. 2005;249:139–47. DOIPubMedGoogle Scholar
  3. Moseley  M, Rahelinirina  S, Rajerison  M, Garin  B, Piertney  S, Telfer  S. Mixed Leptospira infections in a diverse reservoir host community, Madagascar, 2013–2015. Emerg Infect Dis. 2018;24:1138–40. DOIPubMedGoogle Scholar
  4. Kumar  S, Stecher  G, Tamura  K. MEGA7: Molecular Evolutionary Genetics Analysis version 7.0 for bigger datasets. Mol Biol Evol. 2016;33:1870–4. DOIPubMedGoogle Scholar
  5. Perez  J, Goarant  C. Rapid Leptospira identification by direct sequencing of the diagnostic PCR products in New Caledonia. BMC Microbiol. 2010;10:325. DOIPubMedGoogle Scholar
  6. Thomson  JG. Fatal Weil’s disease with myocarditis in South Africa. S Afr Med J. 1964;38:696–700.PubMedGoogle Scholar
  7. Rademan  J, Steytler  JG, Wright  N. First isolations of Leptospirae in Cape Town. S Afr Med J. 1964;38:694–6.PubMedGoogle Scholar
  8. Picardeau  M. Virulence of the zoonotic agent of leptospirosis: still terra incognita? Nat Rev Microbiol. 2017;15:297–307. DOIPubMedGoogle Scholar
  9. Picardeau  M, Bertherat  E, Jancloes  M, Skouloudis  AN, Durski  K, Hartskeerl  RA. Rapid tests for diagnosis of leptospirosis: current tools and emerging technologies. Diagn Microbiol Infect Dis. 2014;78:1–8. DOIPubMedGoogle Scholar
  10. Valarezo-Sevilla  D, Sarzosa-Terán  V. [Leptospirosis: case-series report in a prison of the coast in Ecuador [in Spanish]. Rev Esp Sanid Penit. 2014;16:20–3. DOIPubMedGoogle Scholar

Main Article

Page created: April 16, 2020
Page updated: April 16, 2020
Page reviewed: April 16, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external