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Volume 26, Number 6—June 2020

Dispatch

Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France

Christophe RodriguezComments to Author , Guillaume Gricourt1, Melissa Ndebi1, Vanessa Demontant, Lila Poiteau, Sonia Burrel, David Boutolleau, Paul-Louis Woerther, Vincent Calvez, Sebastian Stroer, and Jean-Michel Pawlotsky
Author affiliations: Henri Mondor Hospital, Assistance Publique des Hôpitaux de Paris at University of Paris-Est, Créteil, France (C. Rodriguez, G. Gricourt, M. Ndebi, V. Demontant, L. Poiteau, P.-L. Woerther, J.-M. Pawlotsky); Pitié-Salpêtrière Hospital, Assistance Publique des Hôpitaux de Paris at Sorbonne-Université, Paris, France (S. Burrel, D. Boutolleau, V. Calvez, S. Stroer)

Main Article

Table

Amino acid differences coded by open reading frames in Cristoli virus compared with Umbre virus*

Open reading frame
Large Medium Small Nonstructural
A16T, M135I, H138Y, Q231L, S249A, R252K, E252D, P318H, V382I, N384T, E408D, V425I, K433R, A452T, R477K, G488E, V566I, V568I, N630S, I792V, V904I, E931S, T939A, R942K, T943S, I966V, V1080I, R1206K, I1444V, G1481D, K1566R, K1662R, D1665H, N1669D, G1987S, AQ2058V, D2074E, N2085D, K2130R, T2168I, T2232S, L2255F, T2258I, G2270E, M2V, V3I, S10L, A12V, L14F, S16N, R32K, D99N, V203I, I332V, A338I, C340Y, V358I, I376V, V382I, K390R, N393S, G427E, R451K, M452L, A458V, I465L, D468N, A473T, A474T, V484I, D504N, K511R, V514E, V515I, S521G, M546V, S578N, T594I, T627A, M692V, N701D, S724L, T746V, P758del, R759del, T760P, K761R, I762V, R772K, S773L, I790V, G791D, V827I, D837E, V839I, S847N, N853D, I860V, S888K, A889T, A904M, V921I, T923M, A967S, V989A, V994I, N996S, I1002M, I1008V, V1020M, T1031A, N1168D, F1206Y, T1254A, T1322M, S1323T, T1378I, T1406A, R1419K, T1443A, A1444T, N1446S F12Y
A53P
T87A
S115N H3R
L52P
R56K

*Differences are indicated using the formula X#Y, where X indicates the presence of an amino acid in Umbre virus, Y a different amino acid in Cristoli virus, and # the position of the difference. A, alanine; C, cysteine; D, aspartic acid; E, glutamic acid; F, phenylalanine; G, glycine; H, histidine; I, isoleucine; K, lysine; L, leucine; M, methionine; N, asparagine; P, proline; Q, glutamine; R, arginine; S, serine; T, threonine; V, vazline; Y, tyrosine.

Main Article

1These authors contributed equally to this article.

Page created: May 19, 2020
Page updated: May 19, 2020
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