Volume 26, Number 6—June 2020
Dispatch
Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France
Table
Amino acid differences coded by open reading frames in Cristoli virus compared with Umbre virus*
Open reading frame |
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---|---|---|---|
Large | Medium | Small | Nonstructural |
A16T, M135I, H138Y, Q231L, S249A, R252K, E252D, P318H, V382I, N384T, E408D, V425I, K433R, A452T, R477K, G488E, V566I, V568I, N630S, I792V, V904I, E931S, T939A, R942K, T943S, I966V, V1080I, R1206K, I1444V, G1481D, K1566R, K1662R, D1665H, N1669D, G1987S, AQ2058V, D2074E, N2085D, K2130R, T2168I, T2232S, L2255F, T2258I, G2270E, | M2V, V3I, S10L, A12V, L14F, S16N, R32K, D99N, V203I, I332V, A338I, C340Y, V358I, I376V, V382I, K390R, N393S, G427E, R451K, M452L, A458V, I465L, D468N, A473T, A474T, V484I, D504N, K511R, V514E, V515I, S521G, M546V, S578N, T594I, T627A, M692V, N701D, S724L, T746V, P758del, R759del, T760P, K761R, I762V, R772K, S773L, I790V, G791D, V827I, D837E, V839I, S847N, N853D, I860V, S888K, A889T, A904M, V921I, T923M, A967S, V989A, V994I, N996S, I1002M, I1008V, V1020M, T1031A, N1168D, F1206Y, T1254A, T1322M, S1323T, T1378I, T1406A, R1419K, T1443A, A1444T, N1446S | F12Y A53P T87A S115N | H3R L52P R56K |
*Differences are indicated using the formula X#Y, where X indicates the presence of an amino acid in Umbre virus, Y a different amino acid in Cristoli virus, and # the position of the difference. A, alanine; C, cysteine; D, aspartic acid; E, glutamic acid; F, phenylalanine; G, glycine; H, histidine; I, isoleucine; K, lysine; L, leucine; M, methionine; N, asparagine; P, proline; Q, glutamine; R, arginine; S, serine; T, threonine; V, vazline; Y, tyrosine.
1These authors contributed equally to this article.