Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 26, Number 6—June 2020

Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France

Christophe RodriguezComments to Author , Guillaume Gricourt1, Melissa Ndebi1, Vanessa Demontant, Lila Poiteau, Sonia Burrel, David Boutolleau, Paul-Louis Woerther, Vincent Calvez, Sebastian Stroer, and Jean-Michel Pawlotsky
Author affiliations: Henri Mondor Hospital, Assistance Publique des Hôpitaux de Paris at University of Paris-Est, Créteil, France (C. Rodriguez, G. Gricourt, M. Ndebi, V. Demontant, L. Poiteau, P.-L. Woerther, J.-M. Pawlotsky); Pitié-Salpêtrière Hospital, Assistance Publique des Hôpitaux de Paris at Sorbonne-Université, Paris, France (S. Burrel, D. Boutolleau, V. Calvez, S. Stroer)

Main Article


Amino acid differences coded by open reading frames in Cristoli virus compared with Umbre virus*

Open reading frame
Large Medium Small Nonstructural
A16T, M135I, H138Y, Q231L, S249A, R252K, E252D, P318H, V382I, N384T, E408D, V425I, K433R, A452T, R477K, G488E, V566I, V568I, N630S, I792V, V904I, E931S, T939A, R942K, T943S, I966V, V1080I, R1206K, I1444V, G1481D, K1566R, K1662R, D1665H, N1669D, G1987S, AQ2058V, D2074E, N2085D, K2130R, T2168I, T2232S, L2255F, T2258I, G2270E, M2V, V3I, S10L, A12V, L14F, S16N, R32K, D99N, V203I, I332V, A338I, C340Y, V358I, I376V, V382I, K390R, N393S, G427E, R451K, M452L, A458V, I465L, D468N, A473T, A474T, V484I, D504N, K511R, V514E, V515I, S521G, M546V, S578N, T594I, T627A, M692V, N701D, S724L, T746V, P758del, R759del, T760P, K761R, I762V, R772K, S773L, I790V, G791D, V827I, D837E, V839I, S847N, N853D, I860V, S888K, A889T, A904M, V921I, T923M, A967S, V989A, V994I, N996S, I1002M, I1008V, V1020M, T1031A, N1168D, F1206Y, T1254A, T1322M, S1323T, T1378I, T1406A, R1419K, T1443A, A1444T, N1446S F12Y
S115N H3R

*Differences are indicated using the formula X#Y, where X indicates the presence of an amino acid in Umbre virus, Y a different amino acid in Cristoli virus, and # the position of the difference. A, alanine; C, cysteine; D, aspartic acid; E, glutamic acid; F, phenylalanine; G, glycine; H, histidine; I, isoleucine; K, lysine; L, leucine; M, methionine; N, asparagine; P, proline; Q, glutamine; R, arginine; S, serine; T, threonine; V, vazline; Y, tyrosine.

Main Article

1These authors contributed equally to this article.

Page created: May 19, 2020
Page updated: May 19, 2020
Page reviewed: May 19, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.