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Volume 26, Number 7—July 2020
Research Letter

Zika Virus Detection with 2013 Serosurvey, Mombasa, Kenya

Elizabeth HunspergerComments to Author , Dennis Odhiambo, Albina Makio, Moshe Alando, Melvin Ochieng, Victor Omballa, Peninah Munyua, Godfrey Bigogo, M. Kariuki Njenga, and Marc-Alain WiddowsonComments to Author 
Author affiliations: US Centers for Disease Control and Prevention, Nairobi, Kenya (E. Hunsperger, P. Munyua, M.-A. Widdowson); Kenya Medical Research Institute, Nairobi, Kenya (D. Odhiambo, A. Makio, M. Alando, M. Ochieng, V. Omballa, G. Bigogo); Washington State University, Pullman, Washington, USA (M.K. Njenga); Institute of Tropical Medicine, Antwerp, Belgium (M.-A. Widdowson)

Main Article

Table

Test results for 16 participants in a 2013 serosurvey in Kenya whose samples were positive for ZIKV by testing conducted in 2018*

Participant no. Age, y CDC ZIKV MAC ELISA P/N ratio (IgM) ZIKV PRNT90 titer DENV PRNT90 titer Participant type Final interpretation of case
2 63 3.56 1:20 <1:20 Serosurvey ZIKV
3 50 10.00 >1:320 <1:20 Serosurvey ZIKV
5 70 3.17 1:20 <1:20 Serosurvey ZIKV
10 NA 3.51 1:20 <1:20 Hospital ZIKV
31 51 5.50 >1:320 1:20 Serosurvey ZIKV
4 45 3.26 <1:20 1:20 Serosurvey DENV
7 36 8.65 1:20 1:320 Serosurvey DENV
20 58 13.18 1:20 1:320 Serosurvey DENV
25 45 3.70 1:20 >1:320 Serosurvey DENV
26 27 5.00 1:80 >1:320 Serosurvey DENV
27 42 3.20 1:80 1:320 Serosurvey DENV
33 30 10.70 1:20 1:80 Serosurvey DENV
1 32 4.49 1:20 1:20 Serosurvey Cross-reactive
9 27 3.82 1:20 1:20 Serosurvey Cross-reactive
30 58 3.20 >1:320 >1:320 Serosurvey Cross-reactive
6 41 16.35 1:20 ND Serosurvey Inconclusive

*CDC, Centers for Disease Control and Prevention; DENV, dengue virus; MAC, IgM antibody capture; NA, not available; ND, not done due to insufficient specimen; PRNT90, plaque reduction neutralization test 90%; ZIKV, Zika virus.

Main Article

Page created: March 18, 2020
Page updated: June 18, 2020
Page reviewed: June 18, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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