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Volume 26, Number 7—July 2020

Dispatch

Clinical Characteristics of Patients Hospitalized with Coronavirus Disease, Thailand

Wannarat A. Pongpirul, Joshua A. Mott, Joseph V. WoodringComments to Author , Timothy M. Uyeki, John R. MacArthur, Apichart Vachiraphan, Pawita Suwanvattana, Sumonmal Uttayamakul, Supamit Chunsuttiwat, Tawee Chotpitayasunondh, Krit Pongpirul, and Wisit Prasithsirikul
Author affiliations: Bamrasnaradura Infectious Diseases Institute, Bangkok, Thailand (W.A. Pongpirul, A. Vachiraphan, P. Suwanvattana, S. Uttayamakul, W. Prasithsirikul); US Centers for Disease Control and Prevention–Thailand Ministry of Public Health Collaboration, Bangkok (J.A. Mott, J.V. Woodring, J.R. MacArthur); US Centers for Disease Control and Prevention, Atlanta, Georgia, USA (T.M. Uyeki); Thailand Ministry of Public Health, Bangkok (S. Chunsuttiwat); Queen Sirikit National Institute for Child Health, Bangkok (T. Chotpitayasunondh); Chulalongkorn University, Bangkok (K. Pongpirul)

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Table 1

Demographics, baseline characteristics, illness histories, laboratory values and treatment therapies of confirmed COVID-19 patients in Bamrasnaradura Infectious Diseases Institute, Bangkok, Thailand, 2020*

Demographics Patient no.
 Total, %
1 2 3 4 5 6 7 8 9 10† 11
Age, y/sex 61/F 74/F 68/M 66/F 57/F 34/M 61/M 63/M 28/F 51/M 49/M 55 M/45 F
Ethnicity CH CH CH CH CH CH CH CH CH TH TH 82 CH/18 TH
Occupation
 Ret
 Ret
 Ret
 Ret
 Ret
 EE
 Ret
 Ret
 Tour guide
 Taxi driver
 Officer
 54 Ret/46 other
Detected through airport screening Y Y Y N N N N N N N N 27 Y/73 N
Detected through contact tracing N N N Y N N N N N N N 9 Y/91 N
Detected after patient voluntarily sought medical care N N N N Y Y Y Y Y Y Y 64 Y/36 N
Visited Hunan Seafood Market
 N
 N
 N
 N
 N
 N
 N
 N
 N
 N
 N
 0
Underlying conditions
Diabetes N N N N N Y N N N Y N 18 Y/82 N
Hypertension Y Y N Y N N N N N Y N 36 Y/64 N
COPD N N N N N N N N N N N 0
Asthma N N N N N N N N N N N 0
Cancer N N N N N N N N N N N 0
Cardiovascular disease N Y N Y N N N Y N N N 27 Y/73 N
Cerebrovascular disease N N N N N N N Y N N N 9 Y/91 N
Chronic liver disease N N N N N N N N N N Y 9 Y/91 N
Any chronic condition
 Y
 Y
 N
 Y
 N
 Y
 N
 Y
 N
 Y
 Y
 64 Y/36 N
Current smoker N N N N N N N N N N N 0
Pregnant
 NA
 NA
 NA
 NA
 NA
 NA
 NA
 NA
 N
 NA
 NA
 0
Laboratory values at time of admission (reference range)
Leukocytes ×109/L (4.5–8) 1.9↓ 3.3↓ 4 3.6 3.9 3.4↓ 5.8 4.1 4.9 5.8 2.5↓
Neutrophils, % (36–70) 48 64 66 63 56 80↑ 63 83 73↑ 58 54
Lymphocytes, % (23–57) 40 19↓ 25 25 33 1↓ 30 16↓ 23 31 30
Platelets ×106 /μL (140–400) 127↓ 16.4↓ 12.6↓ 177 167 169 168 18.4↓ 153 368 167
Hemoglobin, g/dL (11–14) 13.3 12.8 11.5 13.1 13.2 13.3 15.3↑ 13.8 11.4 14 14.8↑
Hematocrit, % (35–41) 38 38 33↓ 37 37.9 38 45↑ 39 34 41 43↑
ALT, U/L (0–31) 18 27 18 83↑ 23 16 22 22 24 24 26
AST, U/L (0–31)
 14
 12
 15
 47↑
 16
 19
 20
 14
 25
 16
 22
Other diagnostics
Oxygen saturation on room air at admission 98 97 95 98 99 99 98 99 96 91↓ 97
Results from Biofire-33 multiplex PCR‡
Haemophilus influenzae + + – – + + – – – – –
Adenovirus – + – – – – – – – – –
Influenza A – – – – – – + – – – –
Klebsiella pneumoniae
 –
 –
 –
 –
 –
 –
 –
 –
 –
 –
 +
Treatments
Antimicrobial drugs, dose
Ceftriaxone, 2 g 4×/d IV 1 0 7 0 0 0 7 0 0 7 0
Ceftriaxone, 2 g/d orally 0 7 0 0 0 0 0 0 0 0 0
AMOX/CLAV, 2 g 4×/d orally 6 0 0 0 0 0 0 0 0 0 7
Oseltamivir, 150 mg 4×/d orally 5 0 0 0 0 0 5 0 0 0 5
Nasal cannula, 5 L, no. days
 0
 0
 0
 0
 0
 0
 0
 0
 0
 3
 0
Duration of signs and symptoms reported at admission, d Median (IQR)/ mean (SD)
Cough 1 1 1 0 2 1 4 2 3 8 5 2 (1–4)/2.5 (2.3)
Malaise or fatigue 4 2 4 0 2 4 13 2 3 5 5 4 (2–5)/4.0 (3.3)
Fever 2 2 4 0 3 4 4 2 2 8 5 3 (2–4)/3.3 (2.1)
Sore throat 4 0 3 0 3 2 4 2 3 7 5 3 (2–4)/3.0 (2.0)
Rhinorrhea 2 2 4 0 2 1 3 2 2 2 4 2 (2–3)/2.2 (1.2)
Headache 1 0 2 0 0 0 0 2 1 5 3 1 (0–2)/1.3 (1.6)
Vomiting 0 1 1 0 0 0 0 1 0 0 0 0 (0–1)/0.3 (0.5)
Diarrhea 0 0 1 0 0 0 0 1 0 0 0 0/0.2 (0.4)

*ALT, alanine aminotransferase; AMOX/CLAV, amoxicillin/clavulanate; AST, aspartate aminotransferase; COVID-19, coronavirus disease; CH, Chinese; EE, electrical engineer; IV, intravenous; NA, not applicable; Ret, retired; TH, Thai; ↓, low; ↑, high; +, positive; –, negative.
†(2)
‡BioFire Diagnostics (https://www.biofiredx.com)

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References
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Page created: April 08, 2020
Page updated: June 18, 2020
Page reviewed: June 18, 2020
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