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Volume 27, Number 12—December 2021
Research Letter

Limited and Short-Lasting Virus Neutralizing Titers Induced by Inactivated SARS-CoV-2 Vaccine

Taweewun Hunsawong, Stefan Fernandez, Rome Buathong, Naretrit Khadthasrima, Kamonthip Rungrojchareonkit, Jindarat Lohachanakul, Rungarun Suthangkornkul, Kedsara Tayong, Angkana T. Huang, Chonticha Klungthong, Piyawan Chinnawirotpisan, Yongyuth Poolpanichupatam, Anthony R. Jones, Eric D. Lombardini, Supaporn Wacharapluesadee, and Opass PutcharoenComments to Author 
Author affiliations: Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand (T. Hunsawong, S. Fernandez, K. Rungrojchareonkit, J. Lohachanakul, R. Suthangkornkul, K. Tayong, A.T. Huang, C. Klungthong, P. Chinnawirotpisan, Y. Poolpanichupatam, A.R. Jones, E.D. Lombardini); Ministry of Public Health, Nonthaburi, Thailand (R. Buathong); Ministry of Public Health, Samut Sakhon Province, Samut Sakhon, Thailand (N. Khadthasrima); Thai Red Cross Emerging Infectious Diseases Clinical Center, Bangkok (S. Wacharapluesadee); Chulalongkorn University Faculty of Medicine, Bangkok (O. Putcharoen)

Main Article

Figure

Results of in vitro testing by microneutralization assay of CoronaVac-induced neutralizing A) Wild-type strain and B) Alpha-, C) Beta-, and D) Delta-variant SARS-CoV-2 antibodies (n = 207). Overall vaccine-induced neutralizing antibodies shown at baseline, 2–3 weeks, and 10–12 weeks after second dose. Differences in mean inhibition rate were compared based on blood collection times. p value <0.05 indicates statistical significance.

Figure. Results of in vitro testing by microneutralization assay of CoronaVac-induced neutralizing A) Wild-type strain and B) Alpha-, C) Beta-, and D) Delta-variant SARS-CoV-2 antibodies (n = 207). Overall vaccine-induced neutralizing antibodies shown at baseline, 2–3 weeks, and 10–12 weeks after second dose. Differences in mean inhibition rate were compared based on blood collection times. p value <0.05 indicates statistical significance.

Main Article

Page created: September 16, 2021
Page updated: November 21, 2021
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