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Volume 27, Number 3—March 2021
Research

Local and Travel-Associated Transmission of Tuberculosis at Central Western Border of Brazil, 2014–2017

Katharine S. Walter1Comments to Author , Mariana Bento Tatara1, Kesia Esther da Silva, Flora Martinez Figueira Moreira, Paulo Cesar Pereira dos Santos, Dândrea Driely de Melo Ferrari, Eunice Atsuko Cunha, Jason R. Andrews2, and Julio Croda2
Author affiliations: Stanford University School of Medicine, Stanford, California, USA (K.S. Walter, K.E. da Silva, J.R. Andrews); Federal University of Grande Dourados, Dourados, Brazil (M.B. Tatara, F.M.F. Moreira, P.C.P. dos Santos, D.D. de Melo Ferrari); Central Laboratory of Public Health, Campo Grande, Brazil (E.A. Cunha); Federal University of Mato Grosso do Sul, Campo Grande, Brazil (J. Croda); Oswaldo Cruz Foundation, Mato Grosso do Sul, Brazil (J. Croda); Yale School of Public Health, New Haven, Connecticut, USA (J. Croda)

Main Article

Figure 2

Unrooted maximum-likelihood phylogeny of 132 Mycobacterium tuberculosis isolates from Central West Brazil, 2014–2017, inferred from a multiple alignment of 6,590 single-nucleotide polymorphisms. From left, columns are colored by patient’s incarceration history, drug-resistance status, city, predicted transmission cluster, and recent travel history. Incarceration history is defined by responses to the study questionnaire and incarceration information in the tuberculosis registry; community includes patients who have not been incarcerated at the time of tuberculosis notification; contact indicates any reported contact with incarcerated persons; formerly incarcerated includes patients who report incarceration prior to their tuberculosis notification; and incarcerated at diagnosis includes patients notified at time of incarceration. Transmission cluster membership is shown for clusters with >4 isolates; all other isolates are labeled as unclustered. Scale bar indicates substitutions per site.

Figure 2. Unrooted maximum-likelihood phylogeny of 132 Mycobacterium tuberculosis isolates from Central West Brazil, 2014–2017, inferred from a multiple alignment of 6,590 single-nucleotide polymorphisms. From left, columns are colored by patient’s incarceration history, drug-resistance status, city, predicted transmission cluster, and recent travel history. Incarceration history is defined by responses to the study questionnaire and incarceration information in the tuberculosis registry; community includes patients who have not been incarcerated at the time of tuberculosis notification; contact indicates any reported contact with incarcerated persons; formerly incarcerated includes patients who report incarceration prior to their tuberculosis notification; and incarcerated at diagnosis includes patients notified at time of incarceration. Transmission cluster membership is shown for clusters with >4 isolates; all other isolates are labeled as unclustered. Scale bar indicates substitutions per site.

Main Article

1These authors contributed equally to this article.

2These authors contributed equally to this article.

Page created: January 20, 2021
Page updated: February 21, 2021
Page reviewed: February 21, 2021
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