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Volume 27, Number 3—March 2021
Research Letter

Local Transmission of SARS-CoV-2 Lineage B.1.1.7, Brazil, December 2020

Ingra Morales Claro1, Flavia Cristina da Silva Sales1, Mariana Severo Ramundo, Darlan S. Candido, Camila A.M. Silva, Jaqueline Goes de Jesus, Erika R. Manuli, Cristina Mendes de Oliveira, Luciano Scarpelli, Gustavo Campana, Oliver G. Pybus, Ester Cerdeira Sabino2, Nuno Rodrigues Faria2, and José Eduardo Levi2Comments to Author 
Author affiliations: University of São Paulo, São Paulo, Brazil (I.M. Claro, F.C.S. Sales, M.S. Ramundo, D.S. Candido, C.A.M. Silva, J.G. de Jesus, E.R. Manuli, E.C. Sabino, N.R. Faria, J.E. Levi); University of Oxford, Oxford, UK (D.S. Candido, O.G. Pybus, N.R. Faria); Diagnósticos da América SA (DASA), Baueri, Brazil (C.M. de Oliveira, L. Scarpelli, G. Campana, J.E. Levi); Imperial College London, London, UK (N.R. Faria)

Main Article

Figure

Phylogenetic context of novel severe acute respiratory syndrome coronavirus 2 B.1.1.7 genomes isolated from 2 patients in Brazil (labeled on figure), December 2020. Downsampling for the phylogenetic analysis of the B.1.1.7 SARS-CoV-2 variant (n = 4,693, December 31, 2020) was performed by selecting 1 sequence per country per day. As outgroups, we included 2 B.1.1 sequences from the United Kingdom that were closely related to the lineage of interest and sequence WH04 from Wuhan, China (GISAID identification no. EPI_ISL_406801; http://www.gisaid.org). Details on multiple alignment and phylogenetic tree reconstruction are described elsewhere (4). Tree file, aligned sequences, and GISAID acknowledgment tables are available at https://github.com/CADDE-CENTRE/VOC-Lineage-Brazil. Scale bar indicates nucleotide substitutions per site. VOC, variant of concern.

Figure. Phylogenetic context of novel severe acute respiratory syndrome coronavirus 2 B.1.1.7 genomes isolated from 2 patients in Brazil (labeled on figure), December 2020. Downsampling for the phylogenetic analysis of the B.1.1.7 SARS-CoV-2 variant (n = 4,693, December 31, 2020) was performed by selecting 1 sequence per country per day. As outgroups, we included 2 B.1.1 sequences from the United Kingdom that were closely related to the lineage of interest and sequence WH04 from Wuhan, China (GISAID identification no. EPI_ISL_406801; http://www.gisaid.org). Details on multiple alignment and phylogenetic tree reconstruction are described elsewhere (4). Tree file, aligned sequences, and GISAID acknowledgment tables are available at https://github.com/CADDE-CENTRE/VOC-Lineage-Brazil. Scale bar indicates nucleotide substitutions per site. VOC, variant of concern.

Main Article

References
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Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

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