Volume 27, Number 4—April 2021
Research Letter
Co-infection with Severe Fever with Thrombocytopenia Syndrome Virus and Rickettsia japonica after Tick Bite, Japan
Tatsuya Fujikawa
, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Shimojima, Masayuki Saijo, and Kyoko Yokota
, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Shimojima, Masayuki Saijo, and Kyoko Yokota
Table
Laboratory findings in patient with severe fever with thrombocytopenia syndrome and positive Rickettsia japonica DNA in eschar at site of tick bite, Japan*
| Parameter | Values | Reference range |
|---|---|---|
| Total blood cell counts | ||
| Leukocytes | 17.1 × 102/µL | 33–86 × 102/μL |
| Erythrocytes | 410 × 104/µL | 380–500 × 104/µL |
| Hemoglobin | 12.4 g/dL | 11.5–15.0 g/dL |
| Hematocrit | 35.2% | 35.0%–45.0% |
| Platelets | 7.4 × 104/µL | 15–35 × 104/μL |
| Neutrophils |
58% |
35.0%–75.0% |
| Coagulation-associated tests | ||
| PT | 10.3 s | 9.9–11.8 s |
| APTT | 45.9 s | 23.0–39.0 s |
| FDP | 4.3 µg/mL | 0.0–5.0 µg/mL |
| D-dimer |
1.2 µg/mL |
0.0–1.0 µg/mL |
| Serum chemistry | ||
| CRP | <1.0 mg/dL | 0.00–0.14 mg/dL |
| AST | 42 U/L | 13–30 U/L |
| ALT | 18 U/L | 7–23 U/L |
| ALP | 170 U/L | 106–322 U/L |
| γ-GT | 14 U/L | 9–32 U/L |
| Total bilirubin | 0.5 mg/dL | 0.4–1.5 mg/dL |
| LDH | 200 U/L | 124–222 U/L |
| CK | 63 U/L | 59–248 U/L |
| Total protein | 7.1 g/dL | 6.6–8.1 g/dL |
| Albumin | 3.9 g/dL | 4.1–5.1 g/dL |
| BUN | 26 mg/dL | 8–20 mg/dL |
| Creatinine | 0.76 mg/dL | 0.46–0.79 mg/dL |
| eGFR | 54.5 mL/min | 80–100 mL/min |
| Ccr | 41.8 mL/min | NA |
| Uric acid | 3.7 mg/dL | 2.6–5.5 mg/dL |
| Sodium | 127 mmol/L | 138–145 mmol/L |
| Potassium | 3.8 mmol/L | 3.6–4.8 mmol/L |
| Chloride | 92 mmol/L | 101–108 mmol/L |
*ALP, alkaline phosphatase; ALT, alanine transaminase; APTT, activated partial thromboplastin time; AST, aspartate transaminase; BUN, blood urea nitrogen; Ccr, calculated creatinine clearance; CK, creatine kinase; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; FDP, fibrin/fibrinogen degradation products; LDH, lactate dehydrogenase; PT, prothrombin time; SFTS, severe fever with thrombocytopenia syndrome; γ-GT, γ-glutamyl transpeptidase.
Page created: March 09, 2021
Page updated: March 19, 2021
Page reviewed: March 19, 2021
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