Clinical Laboratory Perspective on Streptococcus halichoeri, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections
Salika M. Shakir1
, Rahul Gill1
, Jonathan Salberg, E. Susan Slechta, Mark Feldman, Thomas Fritsche, Jill Clarridge, Susan E. Sharp, and Mark A. Fisher
Author affiliations: University of Utah/ARUP Laboratories, Salt Lake City, Utah, USA (S.M. Shakir, M.A. Fisher); Texas Health Presbyterian Hospital of Dallas, Dallas, Texas, USA (R. Gill, M. Feldman); Kaiser Permanente Regional Microbiology and Molecular Infectious Diseases Laboratories, Portland, Oregon, USA (J. Salberg, S.E. Sharp); ARUP Institute for Clinical and Experimental Pathology, Salt Lake City (E.S. Slechta); Marshfield Clinic Health System, Marshfield, Wisconsin, USA (T. Fritsche); University of Washington, Seattle, Washington, USA (J. Clarridge); Copan Diagnostics, Murrieta, California, USA (S.E. Sharp)
Figure 1. Phylogenetic trees based on 16S sequences of clinical and type strains of Streptococcus halichoeri and related taxa from study of human infections caused by unusual strains of S. halichoeri, United States. A) Partial sequences (496 nt); B) full-length sequences (1,434 nt). We generated alignments using ClustalW (http://www.clustal.org), trimmed them to the length of the shortest sequence, and computed neighbor-joining trees with bootstrap analysis with 1,000 replicates using MEGA X (https://www.megasoftware.net). Isolates from case-patients are represented with asterisks (*patient 1; **patient 2). T indicates type strains.
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