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Volume 27, Number 5—May 2021
Research Letter

Risk for International Importations of Variant SARS-CoV-2 Originating in the United Kingdom

Zhanwei Du1, Lin Wang1, Bingyi Yang, Sheikh Taslim Ali, Tim K. Tsang, Songwei Shan, Peng Wu, Eric H.Y. Lau, Benjamin J. Cowling, and Lauren Ancel MeyersComments to Author 
Author affiliations: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, University of Hong Kong, Hong Kong, China (Z. Du, B. Yang, S.T. Ali, T.K. Tsang, S. Shan, P. Wu, E.H.Y. Lau, B.J. Cowling); Laboratory of Data Discovery for Health, Hong Kong (Z. Du, S.T. Ali, S. Shan, P. Wu, E.H.Y. Lau, B.J. Cowling); University of Cambridge, Cambridge, UK (L. Wang); The University of Texas at Austin, Austin, Texas, USA (L.A. Meyers); Santa Fe Institute, Santa Fe, New Mexico, USA (L.A. Meyers)

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Figure

Estimated risks for introduction of the 501Y variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the United Kingdom to 15 other countries before December 7, 2020. A) Probability that >1 person infected with this SARS-CoV-2 variant arrived at the target country from the United Kingdom by the date indicated on the x-axis, based on Facebook mobility data (https://dataforgood.fb.com). The dotted gray vertical line indicates October 28, 2020, the date when the introduction risk for the United States surpassed 50%; line colors correspond to the relative risk for importations as of that date. B) Estimated daily prevalence of the 501Y variant of SARS-CoV-2 in 11 countries between September 22 and December 7, 2020, assuming that the variant is , which means 50% more transmissible than the 501N variant (11). Points and bands indicate means and SDs based on 100 simulations. C) Probability of >1 variant importation by October 28, 2020. Grey indicates countries/regions where mobility data were not available.

Figure. Estimated risks for introduction of the 501Y variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the United Kingdom to 15 other countries before December 7, 2020. A) Probability that >1 person infected with this SARS-CoV-2 variant arrived at the target country from the United Kingdom by the date indicated on the x-axis, based on Facebook mobility data (https://dataforgood.fb.com). The dotted gray vertical line indicates October 28, 2020, the date when the introduction risk for the United States surpassed 50%; line colors correspond to the relative risk for importations as of that date. B) Estimated daily prevalence of the 501Y variant of SARS-CoV-2 in 11 countries between September 22 and December 7, 2020, assuming that the variant is , which means 50% more transmissible than the 501N variant (11). Points and bands indicate means and SDs based on 100 simulations. C) Probability of >1 variant importation by October 28, 2020. Grey indicates countries/regions where mobility data were not available.

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References
  1. Kupferschmidt K. Mutant coronavirus in the United Kingdom sets off alarms, but its importance remains unclear. 2020 Dec 20 [cited 2021 Jan 2]. https://www.sciencemag.org/news/2020/12/mutant-coronavirus-united-kingdom-sets-alarms-its-importance-remains-unclear
  2. Leung  K, Shum  MHH, Leung  GM, Lam  TTY, Wu  JT. Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020. Euro Surveill. 2021;26:2002106. DOIPubMedGoogle Scholar
  3. Kupferschmidt  K. Fast-spreading U.K. virus variant raises alarms. Science. 2021;371:910. DOIPubMedGoogle Scholar
  4. Clark  N, Dathan  M. National lockdown – Boris Johnson orders nation to stay at home until middle of February as 13.5m Brits get Covid jab. 2021 Jan 5 [cited 2021 Jan 7]. https://www.thesun.co.uk/news/politics/13648237/national-lockdown-stay-home-boris-johnson-announcement
  5. BBC News. Coronavirus: Cases of new variant appear worldwide. 2020 Dec 26 [cited 2021 Jan 2]. https://www.bbc.com/news/world-europe-55452262
  6. Centers for Disease Control and Prevention. Emerging SARS-CoV-2 variants. 2020 Dec 29 [cited 2021 Jan 2]. https://www.cdc.gov/coronavirus/2019-ncov/more/science-and-research/scientific-brief-emerging-variants.html
  7. Statista. Number of monthly active Facebook users worldwide as of 4th quarter 2020 [cited 2021 Mar 20]. https://www.statista.com/statistics/264810/number-of-monthly-active-facebook-users- worldwide
  8. Aleta  A, Martín-Corral  D, Pastore Y Piontti  A, Ajelli  M, Litvinova  M, Chinazzi  M, et al. Modelling the impact of testing, contact tracing and household quarantine on second waves of COVID-19. Nat Hum Behav. 2020;4:96471. DOIPubMedGoogle Scholar
  9. International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC). COVID-19 report: 19 [cited 2021 Feb 1]. https://media.tghn.org/medialibrary/2020/05/ISARIC_Data_Platform_COVID-19_Report_19MAY20.pdf
  10. King’s College London. No evidence of change in symptoms from new coronavirus variant. King’s College London. 2021 Feb 1 [cited 2021 Mar 3]. https://www.kcl.ac.uk/news/no-evidence-change-symptoms-new-coronavirus-variant
  11. Davies  NG, Abbott  S, Barnard  RC, Jarvis  CI, Kucharski  AJ, Munday  JD, et al.; CMMID COVID-19 Working Group. COVID-19 Genomics UK (COG-UK) Consortium. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science. 2021;eabg3055; [Epub ahead of print]. DOIGoogle Scholar

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1These first authors contributed equally to this article.

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