Volume 27, Number 6—June 2021
CME ACTIVITY - Synopsis
Rocky Mountain Spotted Fever in a Large Metropolitan Center, Mexico–United States Border, 2009–2019
Table 2
Demographic and clinical characteristics of patients with PCR- and IFA-positive cases of Rocky Mountain spotted fever, Mexicali, Mexico, 2009–2019*
Characteristic | Total | PCR-positive | IFA-positive | p value |
---|---|---|---|---|
No. patients |
759 |
341 |
418 |
|
Sex | ||||
F | 433 (57.05) | 170 (49.85) | 263 (62.92) | <0.001 |
M |
326 (42.95) |
171 (50.15) |
155 (37.08) |
|
Age, y (mean ± SD) | 23.94 (± 17.67) | 24.38 (± 18.89) | 23.59 (± 16.62) | 0.540 |
Hospitalized | 394 (51.91) | 271 (79.47) | 123 (29.43) | <0.001 |
Died |
136 (17.92) |
125 (36.66) |
11 (2.63) |
<0.001 |
Signs and symptoms | ||||
Fever | 759 (100) | 341 (100) | 418 (100) | 0.999 |
Headache | 656 (86.43) | 288 (84.46) | 368 (88.04) | 0.166 |
Myalgia | 468 (61.66) | 229 (67.16) | 239 (57.18) | 0.005 |
Arthralgia | 403 (53.10) | 197 (57.77) | 206 (49.28) | 0.023 |
Retro orbital pain | 82 (10.80) | 26 (7.04) | 58 (13.88) | 0.003 |
Rash | 328 (43.27) | 181 (53.24) | 147 (35.17) | <0.001 |
Pruritis | 139 (18.31) | 56 (16.42) | 83 (19.86) | 0.258 |
Vomiting | 322 (42.42) | 188 (55.13) | 134 (32.06) | <0.001 |
Nausea | 366 (48.22) | 206 (60.41) | 160 (38.28) | <0.001 |
Chills | 274 (36.10) | 127 (37.24) | 147 (35.17) | 0.595 |
Photophobia | 78 (10.28) | 29 (8.50) | 49 (11.72) | 0.152 |
Abdominal pain | 345 (45.45) | 191 (56.01) | 154 (36.84) | <0.001 |
Diarrhea | 188 (24.77) | 112 (32.84) | 76 (18.18) | <0.001 |
Conjunctivitis | 110 (14.49) | 40 (11.73) | 70 (16.75) | 0.062 |
Nasal congestion | 109 (14.36) | 34 (9.97) | 75 (17.94) | 0.002 |
Cough | 189 (24.93) | 72 (21.18) | 117 (27.99) | 0.035 |
Pharyngitis | 156 (20.58) | 69 (20.23) | 87 (20.86) | 0.857 |
Rhinitis | 106 (13.97) | 34 (9.97) | 72 (17.22) | 0.004 |
Hepatomegaly | 68 (8.96) | 44 (12.90) | 24 (5.74) | 0.001 |
Splenomegaly | 31 (4.08) | 21 (6.16) | 10 (2.39) | 0.010 |
Adenomegaly | 17 (2.24) | 7 (2.05) | 10 (2.39) | 0.810 |
Jaundice | 40 (5.27) | 26 (7.62) | 14 (3.35) | 0.013 |
Hemorrhage | 87 (11.46) | 60 (17.60) | 27 (6.46) | <0.001 |
Seizures | 32 (4.22) | 30 (8.80) | 2 (0.48) | <0.001 |
*Values are no. (%) except as indicated. We excluded from these analyses 20 patients who were positive by both assays.