Volume 27, Number 6—June 2021
Melioidosis in Children, Brazil, 1989–2019
||All patients with suspected melioidosis must have epidemiologic exposure at any time, recent or not, associated with >1 of the following criteria: acute febrile illness and respiratory symptoms suggestive of community pneumonia that do not improve with conventional antimicrobial treatment (β-lactam antimicrobial drugs); febrile disease that progresses with systemic inflammatory response syndrome, severe sepsis, or septic shock;
prolonged fever of unknown etiology or signs and symptoms similar to tuberculosis that do not respond to tuberculosis treatment; or soft tissue infection (e.g. cutaneous ulcers/abscesses, cellulite, or fasciitis) of chronic evolution (i.e. months) with no response to conventional antimicrobial treatment (e.g. oxacillin, ampicillin associated to sulbactam, or cefalexin).
||All patients with confirmed melioidosis must meet laboratory (bacteriologic confirmation by microbiological culture or positive PCR) or
clinical-epidemiologic criteria (exposure to the same risk situation as patients with laboratory-confirmed melioidosis). Patients with confirmed melioidosis must have signs and symptoms that are compatible with melioidosis and not attributable to a different cause.
|Severe disease||Patients with severe melioidosis have clinical signs and symptoms and a high risk for death caused by pneumonia, sepsis, or septic shock.|
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1These authors contributed equally to this article.
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