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Volume 27, Number 6—June 2021
Research Letter

Retrospective Identification of Early Autochthonous Case of Crimean-Congo Hemorrhagic Fever, Spain, 2013

Ana Negredo1, María Sánchez-Ledesma1, Francisco Llorente, Mayte Pérez-Olmeda, Moncef Belhassen-García, David González-Calle, María Paz Sánchez-Seco2, and Miguel Ángel Jiménez-Clavero2Comments to Author 
Author affiliations: Instituto de Salud Carlos III, Madrid, Spain (A. Negredo, M.P. Sánchez-Seco, M. Pérez-Olmeda); Hospital Universitario de Salamanca, Salamanca, Spain (M. Sánchez-Ledesma, M. Belhassen-García, D. González-Calle); Animal Health Research Center, INIA-CISA, Valdeolmos, Spain (F. Llorente, M.A. Jiménez-Clavero); Centro de Investigación Biomédica en Red de Epidemiologia y Salud Pública, Madrid (M.A. Jiménez-Clavero)

Main Article


Human cases of Crimean-Congo hemorrhagic fever reported to date, in chronological order, Spain

Year No. cases Autonomous community/province Reference
2013 1 Castile and León/Ávila This study
2016 2 Castile and León/Ávila (index case); community of Madrid/Madrid (secondary case) (3)
2018 2 Extremadura/Badajoz; Castile and León/Salamanca (4)
2020 3 Castile and León/Salamanca (5)

Main Article

  1. Sorvillo  TE, Rodriguez  SE, Hudson  P, Carey  M, Rodriguez  LL, Spiropoulou  CF, et al. Towards a sustainable One Health approach to Crimean-Congo hemorrhagic fever prevention: focus areas and gaps in knowledge. Trop Med Infect Dis. 2020;5:113. DOIPubMedGoogle Scholar
  2. Estrada-Peña  A, Palomar  AM, Santibáñez  P, Sánchez  N, Habela  MA, Portillo  A, et al. Crimean-Congo hemorrhagic fever virus in ticks, Southwestern Europe, 2010. Emerg Infect Dis. 2012;18:17980. DOIPubMedGoogle Scholar
  3. Negredo  A, de la Calle-Prieto  F, Palencia-Herrejón  E, Mora-Rillo  M, Astray-Mochales  J, Sánchez-Seco  MP, et al.; Crimean Congo Hemorrhagic Fever@Madrid Working Group. Autochthonous Crimean-Congo Hemorrhagic Fever in Spain. N Engl J Med. 2017;377:15461. DOIPubMedGoogle Scholar
  4. Coordination Centre for Health Alerts and Emergencies. Ministry of Health. 2020: Report on the situation and risk assessment of transmission of Crimean-Congo hemorrhagic fever (CCHF) virus in Spain [in Spanish] [cited 2020 Nov 11].
  5. Coordination Centre for Health Alerts and Emergencies. Ministry of Health. 2020: Rapid risk assessment. Detection of Crimean-Congo hemorrhagic fever in Salamanca [in Spanish] [cited 2020 Nov 11].
  6. Monsalve Arteaga  L, Muñoz Bellido  JL, Negredo  AI, García Criado  J, Vieira Lista  MC, Sánchez Serrano  , et al. New circulation of genotype V of Crimean-Congo haemorrhagic fever virus in humans from Spain. PLoS Negl Trop Dis. 2021;15:e0009197. DOIPubMedGoogle Scholar

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

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Page updated: May 18, 2021
Page reviewed: May 18, 2021
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