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Volume 27, Number 8—August 2021
Research Letter

Persistence of SARS-CoV-2–Specific IgG in Children 6 Months After Infection, Australia

Zheng Quan Toh, Rachel A. Higgins, Lien Anh Ha Do, Karin Rautenbacher, Francesca L. Mordant, Kanta Subbarao, Kate Dohle, Jill Nguyen, Andrew C. Steer, Shidan Tosif, Nigel W. Crawford, Kim Mulholland, and Paul V. LicciardiComments to Author 
Author affiliations: Murdoch Children’s Research Institute, Melbourne, Victoria, Australia (Z.Q. Toh, R.A. Higgins, L.A.H. Do, K. Dohle, J. Nguyen, A.C. Steer, S. Tosif, N.W. Crawford, K. Mulholland, P.V. Licciardi); The University of Melbourne, Melbourne (Z.Q. Toh, L.A.H. Do, A.C. Steer, S. Tosif, N.W. Crawford, K. Mullholland, P.V. Licciardi); T; he Royal Children’s Hospital, Melbourne (K. Rautenbacher, A.C. Steer, S. Tosif, N.W. Crawford); World Health Organization Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Melbourne (F.L. Mordant, K. Subbarao); London School of Hygiene and Tropical Medicine, London, UK (K. Mulholland)

Main Article

Figure

Persistence of IgG responses against severe acute respiratory syndrome coronavirus 2 in children and adults, Australia, 2020–2021. Patients tested positive by PCR, ELISA, or both. A) Antibody responses of 22 children 0–18 years of age. B) Antibody responses of 32 adults 22–73 years of age. Orange points and lines indicate asymptomatic cases; blue points and lines indicate symptomatic cases in children; green points and lines indicate symptomatic cases in adults. Dotted lines indicate seropositivity cutoff. C) Seropositivity rates in 22 children and 32 adults. Blue points and lines indicate all children, regardless of symptoms; green points and lines indicate all adults, regardless of symptoms. *p<0.05; †p<0.01 (compared with the fist timepoint [day 11]).

Figure. Persistence of IgG responses against severe acute respiratory syndrome coronavirus 2 in children and adults, Australia, 2020–2021. Patients tested positive by PCR, ELISA, or both. A) Antibody responses of 22 children 0–18 years of age. B) Antibody responses of 32 adults 22–73 years of age. Orange points and lines indicate asymptomatic cases; blue points and lines indicate symptomatic cases in children; green points and lines indicate symptomatic cases in adults. Dotted lines indicate seropositivity cutoff. C) Seropositivity rates in 22 children and 32 adults. Blue points and lines indicate all children, regardless of symptoms; green points and lines indicate all adults, regardless of symptoms. *p<0.05; †p<0.01 (compared with the fist timepoint [day 11]).

Main Article

Page created: May 20, 2021
Page updated: July 19, 2021
Page reviewed: July 19, 2021
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